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Table of contents:

  1. Overview

  2. Performance Plots

  3. Performance of RNASampler(20) - scored higher in this pairwise comparison

  4. Performance of ContextFold - scored lower in this pairwise comparison

  5. Compile and download dataset for RNASampler(20) & ContextFold [.zip] - may take several seconds...


Overview

Metric RNASampler(20) ContextFold
MCC 0.582 > 0.567
Average MCC ± 95% Confidence Intervals 0.618 ± 0.419 > 0.596 ± 0.369
Sensitivity 0.506 = 0.506
Positive Predictive Value 0.678 > 0.645
Total TP 40 = 40
Total TN 6862 > 6859
Total FP 34 < 36
Total FP CONTRA 3 < 6
Total FP INCONS 16 = 16
Total FP COMP 15 > 14
Total FN 39 = 39
P-value 0.0

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Performance plots


  1. Comparison of performance of RNASampler(20) and ContextFold. Positive Predictive Value (PPV) is plotted against sensitivity. Each dot represents a single test of each method. See tables below for raw data (individual counts for RNASampler(20) and ContextFold).

  2. Comparison of average Matthews Correlation Coefficients (MCCs) for RNASampler(20) and ContextFold. The whiskers correspond to 95% confidence intervals (CIs). 'n' denotes the number of MCCs used to calculate average MCCs and CIs. See tables below for raw data (individual counts for RNASampler(20) and ContextFold).

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Performance of RNASampler(20) - scored higher in this pairwise comparison

1. Total counts & total scores for RNASampler(20)

Total Base Pair Counts
Total TP 40
Total TN 6862
Total FP 34
Total FP CONTRA 3
Total FP INCONS 16
Total FP COMP 15
Total FN 39
Total Scores
MCC 0.582
Average MCC ± 95% Confidence Intervals 0.618 ± 0.419
Sensitivity 0.506
Positive Predictive Value 0.678
Nr of predictions 4

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2. Individual counts for RNASampler(20) [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
4A1C_2 0.24 0.25 0.24 5 4495 30 3 13 14 15
4AOB_A 0.70 0.59 0.85 17 1417 4 0 3 1 12
4ENB_A 0.68 0.47 1.00 7 465 0 0 0 0 8
4ENC_A 0.85 0.73 1.00 11 485 0 0 0 0 4

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Performance of ContextFold - scored lower in this pairwise comparison

1. Total counts & total scores for ContextFold

Total Base Pair Counts
Total TP 40
Total TN 6859
Total FP 36
Total FP CONTRA 6
Total FP INCONS 16
Total FP COMP 14
Total FN 39
Total Scores
MCC 0.567
Average MCC ± 95% Confidence Intervals 0.596 ± 0.369
Sensitivity 0.506
Positive Predictive Value 0.645
Nr of predictions 4

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2. Individual counts for ContextFold [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
4A1C_2 0.26 0.25 0.28 5 4498 26 3 10 13 15
4AOB_A 0.62 0.59 0.68 17 1412 9 2 6 1 12
4ENB_A 0.77 0.60 1.00 9 463 0 0 0 0 6
4ENC_A 0.73 0.60 0.90 9 486 1 1 0 0 6

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Matthews Correlation Coeffient, Sensitivity and Positive Predictive Value have been calculated based on the paper by Gardener & Giegerich, 2004.