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Table of contents:

  1. Overview

  2. Performance Plots

  3. Performance of RNASampler(20) - scored higher in this pairwise comparison

  4. Performance of PPfold(seed) - scored lower in this pairwise comparison

  5. Compile and download dataset for RNASampler(20) & PPfold(seed) [.zip] - may take several seconds...


Overview

Metric RNASampler(20) PPfold(seed)
MCC 0.693 > 0.036
Average MCC ± 95% Confidence Intervals 0.698 ± 0.253 > 0.016 ± 0.042
Sensitivity 0.606 > 0.008
Positive Predictive Value 0.800 > 0.200
Total TP 80 > 1
Total TN 9220 < 9315
Total FP 35 > 23
Total FP CONTRA 3 > 0
Total FP INCONS 17 > 4
Total FP COMP 15 < 19
Total FN 52 < 131
P-value 0.0

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Performance plots


  1. Comparison of performance of RNASampler(20) and PPfold(seed). Positive Predictive Value (PPV) is plotted against sensitivity. Each dot represents a single test of each method. See tables below for raw data (individual counts for RNASampler(20) and PPfold(seed)).

  2. Comparison of average Matthews Correlation Coefficients (MCCs) for RNASampler(20) and PPfold(seed). The whiskers correspond to 95% confidence intervals (CIs). 'n' denotes the number of MCCs used to calculate average MCCs and CIs. See tables below for raw data (individual counts for RNASampler(20) and PPfold(seed)).

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Performance of RNASampler(20) - scored higher in this pairwise comparison

1. Total counts & total scores for RNASampler(20)

Total Base Pair Counts
Total TP 80
Total TN 9220
Total FP 35
Total FP CONTRA 3
Total FP INCONS 17
Total FP COMP 15
Total FN 52
Total Scores
MCC 0.693
Average MCC ± 95% Confidence Intervals 0.698 ± 0.253
Sensitivity 0.606
Positive Predictive Value 0.800
Nr of predictions 6

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2. Individual counts for RNASampler(20) [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
3RKF_A 0.91 0.83 1.00 20 846 0 0 0 0 4
3SD1_A 0.81 0.69 0.95 20 1512 1 0 1 0 9
4A1C_2 0.24 0.25 0.24 5 4495 30 3 13 14 15
4AOB_A 0.70 0.59 0.85 17 1417 4 0 3 1 12
4ENB_A 0.68 0.47 1.00 7 465 0 0 0 0 8
4ENC_A 0.85 0.73 1.00 11 485 0 0 0 0 4

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Performance of PPfold(seed) - scored lower in this pairwise comparison

1. Total counts & total scores for PPfold(seed)

Total Base Pair Counts
Total TP 1
Total TN 9315
Total FP 23
Total FP CONTRA 0
Total FP INCONS 4
Total FP COMP 19
Total FN 131
Total Scores
MCC 0.036
Average MCC ± 95% Confidence Intervals 0.016 ± 0.042
Sensitivity 0.008
Positive Predictive Value 0.200
Nr of predictions 6

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2. Individual counts for PPfold(seed) [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
3RKF_A 0.00 0.00 0.00 0 866 0 0 0 0 24
3SD1_A 0.00 0.00 0.00 0 1533 0 0 0 0 29
4A1C_2 0.10 0.05 0.20 1 4511 23 0 4 19 19
4AOB_A 0.00 0.00 0.00 0 1437 0 0 0 0 29
4ENB_A 0.00 0.00 0.00 0 472 0 0 0 0 15
4ENC_A 0.00 0.00 0.00 0 496 0 0 0 0 15

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Matthews Correlation Coeffient, Sensitivity and Positive Predictive Value have been calculated based on the paper by Gardener & Giegerich, 2004.