CompaRNA - on-line benchmarks of RNA structure prediction methods
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Table of contents:

  1. Overview

  2. Performance Plots

  3. Performance of RNASampler(20) - scored higher in this pairwise comparison

  4. Performance of RNAwolf - scored lower in this pairwise comparison

  5. Compile and download dataset for RNASampler(20) & RNAwolf [.zip] - may take several seconds...


Overview

Metric RNASampler(20) RNAwolf
MCC 0.693 > 0.442
Average MCC ± 95% Confidence Intervals 0.698 ± 0.253 > 0.439 ± 0.284
Sensitivity 0.606 > 0.439
Positive Predictive Value 0.800 > 0.460
Total TP 80 > 58
Total TN 9220 > 9194
Total FP 35 < 82
Total FP CONTRA 3 < 17
Total FP INCONS 17 < 51
Total FP COMP 15 > 14
Total FN 52 < 74
P-value 0.0

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Performance plots


  1. Comparison of performance of RNASampler(20) and RNAwolf. Positive Predictive Value (PPV) is plotted against sensitivity. Each dot represents a single test of each method. See tables below for raw data (individual counts for RNASampler(20) and RNAwolf).

  2. Comparison of average Matthews Correlation Coefficients (MCCs) for RNASampler(20) and RNAwolf. The whiskers correspond to 95% confidence intervals (CIs). 'n' denotes the number of MCCs used to calculate average MCCs and CIs. See tables below for raw data (individual counts for RNASampler(20) and RNAwolf).

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Performance of RNASampler(20) - scored higher in this pairwise comparison

1. Total counts & total scores for RNASampler(20)

Total Base Pair Counts
Total TP 80
Total TN 9220
Total FP 35
Total FP CONTRA 3
Total FP INCONS 17
Total FP COMP 15
Total FN 52
Total Scores
MCC 0.693
Average MCC ± 95% Confidence Intervals 0.698 ± 0.253
Sensitivity 0.606
Positive Predictive Value 0.800
Nr of predictions 6

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2. Individual counts for RNASampler(20) [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
3RKF_A 0.91 0.83 1.00 20 846 0 0 0 0 4
3SD1_A 0.81 0.69 0.95 20 1512 1 0 1 0 9
4A1C_2 0.24 0.25 0.24 5 4495 30 3 13 14 15
4AOB_A 0.70 0.59 0.85 17 1417 4 0 3 1 12
4ENB_A 0.68 0.47 1.00 7 465 0 0 0 0 8
4ENC_A 0.85 0.73 1.00 11 485 0 0 0 0 4

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Performance of RNAwolf - scored lower in this pairwise comparison

1. Total counts & total scores for RNAwolf

Total Base Pair Counts
Total TP 58
Total TN 9194
Total FP 82
Total FP CONTRA 17
Total FP INCONS 51
Total FP COMP 14
Total FN 74
Total Scores
MCC 0.442
Average MCC ± 95% Confidence Intervals 0.439 ± 0.284
Sensitivity 0.439
Positive Predictive Value 0.460
Nr of predictions 6

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2. Individual counts for RNAwolf [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
3RKF_A 0.89 0.83 0.95 20 845 1 0 1 0 4
3SD1_A 0.58 0.59 0.59 17 1504 12 2 10 0 12
4A1C_2 0.12 0.15 0.10 3 4487 38 12 14 12 17
4AOB_A 0.26 0.24 0.30 7 1414 17 2 14 1 22
4ENB_A 0.45 0.40 0.55 6 461 5 1 4 0 9
4ENC_A 0.34 0.33 0.38 5 483 9 0 8 1 10

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Matthews Correlation Coeffient, Sensitivity and Positive Predictive Value have been calculated based on the paper by Gardener & Giegerich, 2004.