CompaRNA - on-line benchmarks of RNA structure prediction methods
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Table of contents:

  1. Overview

  2. Performance Plots

  3. Performance of RNASampler(seed) - scored higher in this pairwise comparison

  4. Performance of CentroidHomfold‑LAST - scored lower in this pairwise comparison

  5. Compile and download dataset for RNASampler(seed) & CentroidHomfold‑LAST [.zip] - may take several seconds...


Overview

Metric RNASampler(seed) CentroidHomfold‑LAST
MCC 0.559 > 0.517
Average MCC ± 95% Confidence Intervals 0.500 ± 0.651 > 0.461 ± 0.676
Sensitivity 0.484 > 0.462
Positive Predictive Value 0.657 > 0.592
Total TP 44 > 42
Total TN 7376 > 7372
Total FP 31 < 42
Total FP CONTRA 4 < 9
Total FP INCONS 19 < 20
Total FP COMP 8 < 13
Total FN 47 < 49
P-value 0.0

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Performance plots


  1. Comparison of performance of RNASampler(seed) and CentroidHomfold-LAST. Positive Predictive Value (PPV) is plotted against sensitivity. Each dot represents a single test of each method. See tables below for raw data (individual counts for RNASampler(seed) and CentroidHomfold‑LAST).

  2. Comparison of average Matthews Correlation Coefficients (MCCs) for RNASampler(seed) and CentroidHomfold-LAST. The whiskers correspond to 95% confidence intervals (CIs). 'n' denotes the number of MCCs used to calculate average MCCs and CIs. See tables below for raw data (individual counts for RNASampler(seed) and CentroidHomfold‑LAST).

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Performance of RNASampler(seed) - scored higher in this pairwise comparison

1. Total counts & total scores for RNASampler(seed)

Total Base Pair Counts
Total TP 44
Total TN 7376
Total FP 31
Total FP CONTRA 4
Total FP INCONS 19
Total FP COMP 8
Total FN 47
Total Scores
MCC 0.559
Average MCC ± 95% Confidence Intervals 0.500 ± 0.651
Sensitivity 0.484
Positive Predictive Value 0.657
Nr of predictions 4

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2. Individual counts for RNASampler(seed) [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
2LC8_A -0.03 0.00 0.00 0 518 10 0 10 0 18
3RKF_A 0.91 0.83 1.00 20 846 0 0 0 0 4
3SD1_A 0.72 0.55 0.94 16 1516 1 0 1 0 13
4A1C_2 0.40 0.40 0.40 8 4496 20 4 8 8 12

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Performance of CentroidHomfold‑LAST - scored lower in this pairwise comparison

1. Total counts & total scores for CentroidHomfold‑LAST

Total Base Pair Counts
Total TP 42
Total TN 7372
Total FP 42
Total FP CONTRA 9
Total FP INCONS 20
Total FP COMP 13
Total FN 49
Total Scores
MCC 0.517
Average MCC ± 95% Confidence Intervals 0.461 ± 0.676
Sensitivity 0.462
Positive Predictive Value 0.592
Nr of predictions 4

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2. Individual counts for CentroidHomfold‑LAST [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
2LC8_A -0.03 0.00 0.00 0 517 11 0 11 0 18
3RKF_A 0.86 0.75 1.00 18 848 0 0 0 0 6
3SD1_A 0.77 0.66 0.90 19 1512 2 1 1 0 10
4A1C_2 0.24 0.25 0.24 5 4495 29 8 8 13 15

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Matthews Correlation Coeffient, Sensitivity and Positive Predictive Value have been calculated based on the paper by Gardener & Giegerich, 2004.