CompaRNA - on-line benchmarks of RNA structure prediction methods
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Table of contents:

  1. Overview

  2. Performance Plots

  3. Performance of RNASampler(seed) - scored higher in this pairwise comparison

  4. Performance of Fold - scored lower in this pairwise comparison

  5. Compile and download dataset for RNASampler(seed) & Fold [.zip] - may take several seconds...


Overview

Metric RNASampler(seed) Fold
MCC 0.554 > 0.450
Average MCC ± 95% Confidence Intervals 0.507 ± 0.440 > 0.428 ± 0.468
Sensitivity 0.487 < 0.496
Positive Predictive Value 0.640 > 0.418
Total TP 55 < 56
Total TN 12121 > 12073
Total FP 44 < 108
Total FP CONTRA 9 < 27
Total FP INCONS 22 < 51
Total FP COMP 13 < 30
Total FN 58 > 57
P-value 0.0

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Performance plots


  1. Comparison of performance of RNASampler(seed) and Fold. Positive Predictive Value (PPV) is plotted against sensitivity. Each dot represents a single test of each method. See tables below for raw data (individual counts for RNASampler(seed) and Fold).

  2. Comparison of average Matthews Correlation Coefficients (MCCs) for RNASampler(seed) and Fold. The whiskers correspond to 95% confidence intervals (CIs). 'n' denotes the number of MCCs used to calculate average MCCs and CIs. See tables below for raw data (individual counts for RNASampler(seed) and Fold).

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Performance of RNASampler(seed) - scored higher in this pairwise comparison

1. Total counts & total scores for RNASampler(seed)

Total Base Pair Counts
Total TP 55
Total TN 12121
Total FP 44
Total FP CONTRA 9
Total FP INCONS 22
Total FP COMP 13
Total FN 58
Total Scores
MCC 0.554
Average MCC ± 95% Confidence Intervals 0.507 ± 0.440
Sensitivity 0.487
Positive Predictive Value 0.640
Nr of predictions 5

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2. Individual counts for RNASampler(seed) [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
2LC8_A -0.03 0.00 0.00 0 518 10 0 10 0 18
3O58_3 0.54 0.50 0.58 11 4745 13 5 3 5 11
3RKF_A 0.91 0.83 1.00 20 846 0 0 0 0 4
3SD1_A 0.72 0.55 0.94 16 1516 1 0 1 0 13
4A1C_2 0.40 0.40 0.40 8 4496 20 4 8 8 12

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Performance of Fold - scored lower in this pairwise comparison

1. Total counts & total scores for Fold

Total Base Pair Counts
Total TP 56
Total TN 12073
Total FP 108
Total FP CONTRA 27
Total FP INCONS 51
Total FP COMP 30
Total FN 57
Total Scores
MCC 0.450
Average MCC ± 95% Confidence Intervals 0.428 ± 0.468
Sensitivity 0.496
Positive Predictive Value 0.418
Nr of predictions 5

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2. Individual counts for Fold [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
2LC8_A -0.03 0.00 0.00 0 513 15 3 12 0 18
3O58_3 0.39 0.50 0.31 11 4728 41 9 16 16 11
3RKF_A 0.91 0.83 1.00 20 846 0 0 0 0 4
3SD1_A 0.68 0.69 0.69 20 1504 9 4 5 0 9
4A1C_2 0.19 0.25 0.15 5 4482 43 11 18 14 15

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Matthews Correlation Coeffient, Sensitivity and Positive Predictive Value have been calculated based on the paper by Gardener & Giegerich, 2004.