CompaRNA - on-line benchmarks of RNA structure prediction methods
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Table of contents:

  1. Overview

  2. Performance Plots

  3. Performance of RNASampler(seed) - scored higher in this pairwise comparison

  4. Performance of MXScarna(20) - scored lower in this pairwise comparison

  5. Compile and download dataset for RNASampler(seed) & MXScarna(20) [.zip] - may take several seconds...


Overview

Metric RNASampler(seed) MXScarna(20)
MCC 0.696 > 0.652
Average MCC ± 95% Confidence Intervals 0.694 ± 0.282 > 0.651 ± 0.317
Sensitivity 0.627 < 0.636
Positive Predictive Value 0.779 > 0.676
Total TP 74 < 75
Total TN 12487 > 12471
Total FP 34 < 65
Total FP CONTRA 9 < 21
Total FP INCONS 12 < 15
Total FP COMP 13 < 29
Total FN 44 > 43
P-value 0.0

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Performance plots


  1. Comparison of performance of RNASampler(seed) and MXScarna(20). Positive Predictive Value (PPV) is plotted against sensitivity. Each dot represents a single test of each method. See tables below for raw data (individual counts for RNASampler(seed) and MXScarna(20)).

  2. Comparison of average Matthews Correlation Coefficients (MCCs) for RNASampler(seed) and MXScarna(20). The whiskers correspond to 95% confidence intervals (CIs). 'n' denotes the number of MCCs used to calculate average MCCs and CIs. See tables below for raw data (individual counts for RNASampler(seed) and MXScarna(20)).

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Performance of RNASampler(seed) - scored higher in this pairwise comparison

1. Total counts & total scores for RNASampler(seed)

Total Base Pair Counts
Total TP 74
Total TN 12487
Total FP 34
Total FP CONTRA 9
Total FP INCONS 12
Total FP COMP 13
Total FN 44
Total Scores
MCC 0.696
Average MCC ± 95% Confidence Intervals 0.694 ± 0.282
Sensitivity 0.627
Positive Predictive Value 0.779
Nr of predictions 5

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2. Individual counts for RNASampler(seed) [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
3IVN_B 0.91 0.83 1.00 19 884 0 0 0 0 4
3O58_3 0.54 0.50 0.58 11 4745 13 5 3 5 11
3RKF_A 0.91 0.83 1.00 20 846 0 0 0 0 4
3SD1_A 0.72 0.55 0.94 16 1516 1 0 1 0 13
4A1C_2 0.40 0.40 0.40 8 4496 20 4 8 8 12

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Performance of MXScarna(20) - scored lower in this pairwise comparison

1. Total counts & total scores for MXScarna(20)

Total Base Pair Counts
Total TP 75
Total TN 12471
Total FP 65
Total FP CONTRA 21
Total FP INCONS 15
Total FP COMP 29
Total FN 43
Total Scores
MCC 0.652
Average MCC ± 95% Confidence Intervals 0.651 ± 0.317
Sensitivity 0.636
Positive Predictive Value 0.676
Nr of predictions 5

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2. Individual counts for MXScarna(20) [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
3IVN_B 0.81 0.74 0.89 17 884 2 2 0 0 6
3O58_3 0.62 0.59 0.65 13 4744 18 5 2 11 9
3RKF_A 0.86 0.75 1.00 18 848 0 0 0 0 6
3SD1_A 0.74 0.76 0.73 22 1503 9 6 2 1 7
4A1C_2 0.22 0.25 0.21 5 4492 36 8 11 17 15

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Matthews Correlation Coeffient, Sensitivity and Positive Predictive Value have been calculated based on the paper by Gardener & Giegerich, 2004.