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Table of contents:

  1. Overview

  2. Performance Plots

  3. Performance of RNASampler(seed) - scored higher in this pairwise comparison

  4. Performance of Multilign(20) - scored lower in this pairwise comparison

  5. Compile and download dataset for RNASampler(seed) & Multilign(20) [.zip] - may take several seconds...


Overview

Metric RNASampler(seed) Multilign(20)
MCC 0.679 > 0.590
Average MCC ± 95% Confidence Intervals 0.675 ± 0.644 > 0.597 ± 0.908
Sensitivity 0.603 < 0.630
Positive Predictive Value 0.772 > 0.561
Total TP 44 < 46
Total TN 6858 > 6833
Total FP 21 < 43
Total FP CONTRA 4 < 13
Total FP INCONS 9 < 23
Total FP COMP 8 > 7
Total FN 29 > 27
P-value 0.0

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Performance plots


  1. Comparison of performance of RNASampler(seed) and Multilign(20). Positive Predictive Value (PPV) is plotted against sensitivity. Each dot represents a single test of each method. See tables below for raw data (individual counts for RNASampler(seed) and Multilign(20)).

  2. Comparison of average Matthews Correlation Coefficients (MCCs) for RNASampler(seed) and Multilign(20). The whiskers correspond to 95% confidence intervals (CIs). 'n' denotes the number of MCCs used to calculate average MCCs and CIs. See tables below for raw data (individual counts for RNASampler(seed) and Multilign(20)).

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Performance of RNASampler(seed) - scored higher in this pairwise comparison

1. Total counts & total scores for RNASampler(seed)

Total Base Pair Counts
Total TP 44
Total TN 6858
Total FP 21
Total FP CONTRA 4
Total FP INCONS 9
Total FP COMP 8
Total FN 29
Total Scores
MCC 0.679
Average MCC ± 95% Confidence Intervals 0.675 ± 0.644
Sensitivity 0.603
Positive Predictive Value 0.772
Nr of predictions 3

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2. Individual counts for RNASampler(seed) [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
3RKF_A 0.91 0.83 1.00 20 846 0 0 0 0 4
3SD1_A 0.72 0.55 0.94 16 1516 1 0 1 0 13
4A1C_2 0.40 0.40 0.40 8 4496 20 4 8 8 12

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Performance of Multilign(20) - scored lower in this pairwise comparison

1. Total counts & total scores for Multilign(20)

Total Base Pair Counts
Total TP 46
Total TN 6833
Total FP 43
Total FP CONTRA 13
Total FP INCONS 23
Total FP COMP 7
Total FN 27
Total Scores
MCC 0.590
Average MCC ± 95% Confidence Intervals 0.597 ± 0.908
Sensitivity 0.630
Positive Predictive Value 0.561
Nr of predictions 3

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2. Individual counts for Multilign(20) [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
3RKF_A 0.91 0.88 0.95 21 844 1 0 1 0 3
3SD1_A 0.68 0.69 0.69 20 1504 9 4 5 0 9
4A1C_2 0.20 0.25 0.16 5 4485 33 9 17 7 15

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Matthews Correlation Coeffient, Sensitivity and Positive Predictive Value have been calculated based on the paper by Gardener & Giegerich, 2004.