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Table of contents:

  1. Overview

  2. Performance Plots

  3. Performance of RNASampler(seed) - scored higher in this pairwise comparison

  4. Performance of Murlet(20) - scored lower in this pairwise comparison

  5. Compile and download dataset for RNASampler(seed) & Murlet(20) [.zip] - may take several seconds...


Overview

Metric RNASampler(seed) Murlet(20)
MCC 0.696 > 0.610
Average MCC ± 95% Confidence Intervals 0.694 ± 0.282 > 0.606 ± 0.359
Sensitivity 0.627 > 0.568
Positive Predictive Value 0.779 > 0.663
Total TP 74 > 67
Total TN 12487 > 12481
Total FP 34 < 42
Total FP CONTRA 9 < 13
Total FP INCONS 12 < 21
Total FP COMP 13 > 8
Total FN 44 < 51
P-value 0.0

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Performance plots


  1. Comparison of performance of RNASampler(seed) and Murlet(20). Positive Predictive Value (PPV) is plotted against sensitivity. Each dot represents a single test of each method. See tables below for raw data (individual counts for RNASampler(seed) and Murlet(20)).

  2. Comparison of average Matthews Correlation Coefficients (MCCs) for RNASampler(seed) and Murlet(20). The whiskers correspond to 95% confidence intervals (CIs). 'n' denotes the number of MCCs used to calculate average MCCs and CIs. See tables below for raw data (individual counts for RNASampler(seed) and Murlet(20)).

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Performance of RNASampler(seed) - scored higher in this pairwise comparison

1. Total counts & total scores for RNASampler(seed)

Total Base Pair Counts
Total TP 74
Total TN 12487
Total FP 34
Total FP CONTRA 9
Total FP INCONS 12
Total FP COMP 13
Total FN 44
Total Scores
MCC 0.696
Average MCC ± 95% Confidence Intervals 0.694 ± 0.282
Sensitivity 0.627
Positive Predictive Value 0.779
Nr of predictions 5

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2. Individual counts for RNASampler(seed) [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
3IVN_B 0.91 0.83 1.00 19 884 0 0 0 0 4
3O58_3 0.54 0.50 0.58 11 4745 13 5 3 5 11
3RKF_A 0.91 0.83 1.00 20 846 0 0 0 0 4
3SD1_A 0.72 0.55 0.94 16 1516 1 0 1 0 13
4A1C_2 0.40 0.40 0.40 8 4496 20 4 8 8 12

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Performance of Murlet(20) - scored lower in this pairwise comparison

1. Total counts & total scores for Murlet(20)

Total Base Pair Counts
Total TP 67
Total TN 12481
Total FP 42
Total FP CONTRA 13
Total FP INCONS 21
Total FP COMP 8
Total FN 51
Total Scores
MCC 0.610
Average MCC ± 95% Confidence Intervals 0.606 ± 0.359
Sensitivity 0.568
Positive Predictive Value 0.663
Nr of predictions 5

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2. Individual counts for Murlet(20) [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
3IVN_B 0.80 0.65 1.00 15 888 0 0 0 0 8
3O58_3 0.37 0.32 0.44 7 4748 13 4 5 4 15
3RKF_A 0.81 0.67 1.00 16 850 0 0 0 0 8
3SD1_A 0.82 0.83 0.83 24 1504 5 4 1 0 5
4A1C_2 0.22 0.25 0.20 5 4491 24 5 15 4 15

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Matthews Correlation Coeffient, Sensitivity and Positive Predictive Value have been calculated based on the paper by Gardener & Giegerich, 2004.