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Table of contents:

  1. Overview

  2. Performance Plots

  3. Performance of RNASampler(seed) - scored higher in this pairwise comparison

  4. Performance of NanoFolder - scored lower in this pairwise comparison

  5. Compile and download dataset for RNASampler(seed) & NanoFolder [.zip] - may take several seconds...


Overview

Metric RNASampler(seed) NanoFolder
MCC 0.232 > 0.207
Average MCC ± 95% Confidence Intervals 0.186 ± 2.685 < 0.264 ± 3.446
Sensitivity 0.211 < 0.289
Positive Predictive Value 0.267 > 0.159
Total TP 8 < 11
Total TN 5014 > 4975
Total FP 30 < 72
Total FP CONTRA 4 < 19
Total FP INCONS 18 < 39
Total FP COMP 8 < 14
Total FN 30 > 27
P-value 0.0

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Performance plots


  1. Comparison of performance of RNASampler(seed) and NanoFolder. Positive Predictive Value (PPV) is plotted against sensitivity. Each dot represents a single test of each method. See tables below for raw data (individual counts for RNASampler(seed) and NanoFolder).

  2. Comparison of average Matthews Correlation Coefficients (MCCs) for RNASampler(seed) and NanoFolder. The whiskers correspond to 95% confidence intervals (CIs). 'n' denotes the number of MCCs used to calculate average MCCs and CIs. See tables below for raw data (individual counts for RNASampler(seed) and NanoFolder).

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Performance of RNASampler(seed) - scored higher in this pairwise comparison

1. Total counts & total scores for RNASampler(seed)

Total Base Pair Counts
Total TP 8
Total TN 5014
Total FP 30
Total FP CONTRA 4
Total FP INCONS 18
Total FP COMP 8
Total FN 30
Total Scores
MCC 0.232
Average MCC ± 95% Confidence Intervals 0.186 ± 2.685
Sensitivity 0.211
Positive Predictive Value 0.267
Nr of predictions 2

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2. Individual counts for RNASampler(seed) [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
2LC8_A

GP_knot1 links to Rfam database...

-0.03 0.00 0.00 0 518 10 0 10 0 18
4A1C_2

5_8S_rRNA links to Rfam database...

0.40 0.40 0.40 8 4496 20 4 8 8 12

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Performance of NanoFolder - scored lower in this pairwise comparison

1. Total counts & total scores for NanoFolder

Total Base Pair Counts
Total TP 11
Total TN 4975
Total FP 72
Total FP CONTRA 19
Total FP INCONS 39
Total FP COMP 14
Total FN 27
Total Scores
MCC 0.207
Average MCC ± 95% Confidence Intervals 0.264 ± 3.446
Sensitivity 0.289
Positive Predictive Value 0.159
Nr of predictions 2

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2. Individual counts for NanoFolder [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
2LC8_A

GP_knot1 links to Rfam database...

0.54 0.61 0.50 11 506 11 1 10 0 7
4A1C_2

5_8S_rRNA links to Rfam database...

-0.01 0.00 0.00 0 4469 61 18 29 14 20

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Matthews Correlation Coeffient, Sensitivity and Positive Predictive Value have been calculated based on the paper by Gardener & Giegerich, 2004.

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