CompaRNA - on-line benchmarks of RNA structure prediction methods
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Table of contents:

  1. Overview

  2. Performance Plots

  3. Performance of RNASampler(seed) - scored higher in this pairwise comparison

  4. Performance of RDfolder - scored lower in this pairwise comparison

  5. Compile and download dataset for RNASampler(seed) & RDfolder [.zip] - may take several seconds...


Overview

Metric RNASampler(seed) RDfolder
MCC 0.710 > 0.579
Average MCC ± 95% Confidence Intervals 0.656 ± 0.484 > 0.546 ± 0.494
Sensitivity 0.589 > 0.492
Positive Predictive Value 0.869 > 0.701
Total TP 73 > 61
Total TN 5246 > 5243
Total FP 11 < 26
Total FP CONTRA 0 < 4
Total FP INCONS 11 < 22
Total FP COMP 0 = 0
Total FN 51 < 63
P-value 0.0

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Performance plots


  1. Comparison of performance of RNASampler(seed) and RDfolder. Positive Predictive Value (PPV) is plotted against sensitivity. Each dot represents a single test of each method. See tables below for raw data (individual counts for RNASampler(seed) and RDfolder).

  2. Comparison of average Matthews Correlation Coefficients (MCCs) for RNASampler(seed) and RDfolder. The whiskers correspond to 95% confidence intervals (CIs). 'n' denotes the number of MCCs used to calculate average MCCs and CIs. See tables below for raw data (individual counts for RNASampler(seed) and RDfolder).

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Performance of RNASampler(seed) - scored higher in this pairwise comparison

1. Total counts & total scores for RNASampler(seed)

Total Base Pair Counts
Total TP 73
Total TN 5246
Total FP 11
Total FP CONTRA 0
Total FP INCONS 11
Total FP COMP 0
Total FN 51
Total Scores
MCC 0.710
Average MCC ± 95% Confidence Intervals 0.656 ± 0.484
Sensitivity 0.589
Positive Predictive Value 0.869
Nr of predictions 5

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2. Individual counts for RNASampler(seed) [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
2LC8_A -0.03 0.00 0.00 0 518 10 0 10 0 18
3A3A_A 0.77 0.60 1.00 18 1482 0 0 0 0 12
3IVN_B 0.91 0.83 1.00 19 884 0 0 0 0 4
3RKF_A 0.91 0.83 1.00 20 846 0 0 0 0 4
3SD1_A 0.72 0.55 0.94 16 1516 1 0 1 0 13

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Performance of RDfolder - scored lower in this pairwise comparison

1. Total counts & total scores for RDfolder

Total Base Pair Counts
Total TP 61
Total TN 5243
Total FP 26
Total FP CONTRA 4
Total FP INCONS 22
Total FP COMP 0
Total FN 63
Total Scores
MCC 0.579
Average MCC ± 95% Confidence Intervals 0.546 ± 0.494
Sensitivity 0.492
Positive Predictive Value 0.701
Nr of predictions 5

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2. Individual counts for RDfolder [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
2LC8_A -0.03 0.00 0.00 0 514 14 3 11 0 18
3A3A_A 0.59 0.50 0.71 15 1479 6 0 6 0 15
3IVN_B 0.91 0.83 1.00 19 884 0 0 0 0 4
3RKF_A 0.91 0.83 1.00 20 846 0 0 0 0 4
3SD1_A 0.35 0.24 0.54 7 1520 6 1 5 0 22

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Matthews Correlation Coeffient, Sensitivity and Positive Predictive Value have been calculated based on the paper by Gardener & Giegerich, 2004.