CompaRNA - on-line benchmarks of RNA structure prediction methods
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Table of contents:

  1. Overview

  2. Performance Plots

  3. Performance of RNASampler(seed) - scored higher in this pairwise comparison

  4. Performance of RNAalifold(20) - scored lower in this pairwise comparison

  5. Compile and download dataset for RNASampler(seed) & RNAalifold(20) [.zip] - may take several seconds...


Overview

Metric RNASampler(seed) RNAalifold(20)
MCC 0.696 > 0.640
Average MCC ± 95% Confidence Intervals 0.694 ± 0.282 > 0.631 ± 0.365
Sensitivity 0.627 > 0.619
Positive Predictive Value 0.779 > 0.670
Total TP 74 > 73
Total TN 12487 > 12473
Total FP 34 < 39
Total FP CONTRA 9 < 13
Total FP INCONS 12 < 23
Total FP COMP 13 > 3
Total FN 44 < 45
P-value 0.0

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Performance plots


  1. Comparison of performance of RNASampler(seed) and RNAalifold(20). Positive Predictive Value (PPV) is plotted against sensitivity. Each dot represents a single test of each method. See tables below for raw data (individual counts for RNASampler(seed) and RNAalifold(20)).

  2. Comparison of average Matthews Correlation Coefficients (MCCs) for RNASampler(seed) and RNAalifold(20). The whiskers correspond to 95% confidence intervals (CIs). 'n' denotes the number of MCCs used to calculate average MCCs and CIs. See tables below for raw data (individual counts for RNASampler(seed) and RNAalifold(20)).

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Performance of RNASampler(seed) - scored higher in this pairwise comparison

1. Total counts & total scores for RNASampler(seed)

Total Base Pair Counts
Total TP 74
Total TN 12487
Total FP 34
Total FP CONTRA 9
Total FP INCONS 12
Total FP COMP 13
Total FN 44
Total Scores
MCC 0.696
Average MCC ± 95% Confidence Intervals 0.694 ± 0.282
Sensitivity 0.627
Positive Predictive Value 0.779
Nr of predictions 5

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2. Individual counts for RNASampler(seed) [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
3IVN_B 0.91 0.83 1.00 19 884 0 0 0 0 4
3O58_3 0.54 0.50 0.58 11 4745 13 5 3 5 11
3RKF_A 0.91 0.83 1.00 20 846 0 0 0 0 4
3SD1_A 0.72 0.55 0.94 16 1516 1 0 1 0 13
4A1C_2 0.40 0.40 0.40 8 4496 20 4 8 8 12

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Performance of RNAalifold(20) - scored lower in this pairwise comparison

1. Total counts & total scores for RNAalifold(20)

Total Base Pair Counts
Total TP 73
Total TN 12473
Total FP 39
Total FP CONTRA 13
Total FP INCONS 23
Total FP COMP 3
Total FN 45
Total Scores
MCC 0.640
Average MCC ± 95% Confidence Intervals 0.631 ± 0.365
Sensitivity 0.619
Positive Predictive Value 0.670
Nr of predictions 5

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2. Individual counts for RNAalifold(20) [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
3IVN_B 0.86 0.78 0.95 18 884 1 1 0 0 5
3O58_3 0.42 0.36 0.50 8 4748 9 3 5 1 14
3RKF_A 0.81 0.71 0.94 17 848 1 0 1 0 7
3SD1_A 0.84 0.86 0.83 25 1503 5 4 1 0 4
4A1C_2 0.22 0.25 0.19 5 4490 23 5 16 2 15

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Matthews Correlation Coeffient, Sensitivity and Positive Predictive Value have been calculated based on the paper by Gardener & Giegerich, 2004.