CompaRNA - on-line benchmarks of RNA structure prediction methods
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Table of contents:

  1. Overview

  2. Performance Plots

  3. Performance of RNASampler(seed) - scored higher in this pairwise comparison

  4. Performance of TurboFold(seed) - scored lower in this pairwise comparison

  5. Compile and download dataset for RNASampler(seed) & TurboFold(seed) [.zip] - may take several seconds...


Overview

Metric RNASampler(seed) TurboFold(seed)
MCC 0.559 > 0.486
Average MCC ± 95% Confidence Intervals 0.500 ± 0.651 > 0.447 ± 0.696
Sensitivity 0.484 < 0.495
Positive Predictive Value 0.657 > 0.489
Total TP 44 < 45
Total TN 7376 > 7351
Total FP 31 < 59
Total FP CONTRA 4 < 14
Total FP INCONS 19 < 33
Total FP COMP 8 < 12
Total FN 47 > 46
P-value 0.0

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Performance plots


  1. Comparison of performance of RNASampler(seed) and TurboFold(seed). Positive Predictive Value (PPV) is plotted against sensitivity. Each dot represents a single test of each method. See tables below for raw data (individual counts for RNASampler(seed) and TurboFold(seed)).

  2. Comparison of average Matthews Correlation Coefficients (MCCs) for RNASampler(seed) and TurboFold(seed). The whiskers correspond to 95% confidence intervals (CIs). 'n' denotes the number of MCCs used to calculate average MCCs and CIs. See tables below for raw data (individual counts for RNASampler(seed) and TurboFold(seed)).

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Performance of RNASampler(seed) - scored higher in this pairwise comparison

1. Total counts & total scores for RNASampler(seed)

Total Base Pair Counts
Total TP 44
Total TN 7376
Total FP 31
Total FP CONTRA 4
Total FP INCONS 19
Total FP COMP 8
Total FN 47
Total Scores
MCC 0.559
Average MCC ± 95% Confidence Intervals 0.500 ± 0.651
Sensitivity 0.484
Positive Predictive Value 0.657
Nr of predictions 4

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2. Individual counts for RNASampler(seed) [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
2LC8_A -0.03 0.00 0.00 0 518 10 0 10 0 18
3RKF_A 0.91 0.83 1.00 20 846 0 0 0 0 4
3SD1_A 0.72 0.55 0.94 16 1516 1 0 1 0 13
4A1C_2 0.40 0.40 0.40 8 4496 20 4 8 8 12

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Performance of TurboFold(seed) - scored lower in this pairwise comparison

1. Total counts & total scores for TurboFold(seed)

Total Base Pair Counts
Total TP 45
Total TN 7351
Total FP 59
Total FP CONTRA 14
Total FP INCONS 33
Total FP COMP 12
Total FN 46
Total Scores
MCC 0.486
Average MCC ± 95% Confidence Intervals 0.447 ± 0.696
Sensitivity 0.495
Positive Predictive Value 0.489
Nr of predictions 4

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2. Individual counts for TurboFold(seed) [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
2LC8_A -0.03 0.00 0.00 0 513 15 3 12 0 18
3RKF_A 0.91 0.83 1.00 20 846 0 0 0 0 4
3SD1_A 0.71 0.69 0.74 20 1506 7 2 5 0 9
4A1C_2 0.20 0.25 0.17 5 4486 37 9 16 12 15

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Matthews Correlation Coeffient, Sensitivity and Positive Predictive Value have been calculated based on the paper by Gardener & Giegerich, 2004.