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Table of contents:

  1. Overview

  2. Performance Plots

  3. Performance of RNAalifold(seed) - scored higher in this pairwise comparison

  4. Performance of RNASLOpt - scored lower in this pairwise comparison

  5. Compile and download dataset for RNAalifold(seed) & RNASLOpt [.zip] - may take several seconds...


Overview

Metric RNAalifold(seed) RNASLOpt
MCC 0.542 > 0.461
Average MCC ± 95% Confidence Intervals 0.515 ± 0.408 < 0.536 ± 0.307
Sensitivity 0.392 < 0.443
Positive Predictive Value 0.760 > 0.494
Total TP 38 < 43
Total TN 7399 > 7362
Total FP 16 < 53
Total FP CONTRA 0 < 17
Total FP INCONS 12 < 27
Total FP COMP 4 < 9
Total FN 59 > 54
P-value 0.0

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Performance plots


  1. Comparison of performance of RNAalifold(seed) and RNASLOpt. Positive Predictive Value (PPV) is plotted against sensitivity. Each dot represents a single test of each method. See tables below for raw data (individual counts for RNAalifold(seed) and RNASLOpt).

  2. Comparison of average Matthews Correlation Coefficients (MCCs) for RNAalifold(seed) and RNASLOpt. The whiskers correspond to 95% confidence intervals (CIs). 'n' denotes the number of MCCs used to calculate average MCCs and CIs. See tables below for raw data (individual counts for RNAalifold(seed) and RNASLOpt).

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Performance of RNAalifold(seed) - scored higher in this pairwise comparison

1. Total counts & total scores for RNAalifold(seed)

Total Base Pair Counts
Total TP 38
Total TN 7399
Total FP 16
Total FP CONTRA 0
Total FP INCONS 12
Total FP COMP 4
Total FN 59
Total Scores
MCC 0.542
Average MCC ± 95% Confidence Intervals 0.515 ± 0.408
Sensitivity 0.392
Positive Predictive Value 0.760
Nr of predictions 5

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2. Individual counts for RNAalifold(seed) [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
2LC8_A -0.03 0.00 0.00 0 516 12 0 12 0 18
4A1C_2 0.50 0.25 1.00 5 4511 2 0 0 2 15
4AOB_A 0.85 0.72 1.00 21 1416 2 0 0 2 8
4ENB_A 0.63 0.40 1.00 6 466 0 0 0 0 9
4ENC_A 0.63 0.40 1.00 6 490 0 0 0 0 9

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Performance of RNASLOpt - scored lower in this pairwise comparison

1. Total counts & total scores for RNASLOpt

Total Base Pair Counts
Total TP 43
Total TN 7362
Total FP 53
Total FP CONTRA 17
Total FP INCONS 27
Total FP COMP 9
Total FN 54
Total Scores
MCC 0.461
Average MCC ± 95% Confidence Intervals 0.536 ± 0.307
Sensitivity 0.443
Positive Predictive Value 0.494
Nr of predictions 5

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2. Individual counts for RNASLOpt [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
2LC8_A 0.48 0.39 0.64 7 517 4 0 4 0 11
4A1C_2 0.30 0.40 0.24 8 4482 35 13 13 9 12
4AOB_A 0.31 0.28 0.38 8 1416 13 3 10 0 21
4ENB_A 0.85 0.73 1.00 11 461 0 0 0 0 4
4ENC_A 0.73 0.60 0.90 9 486 1 1 0 0 6

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Matthews Correlation Coeffient, Sensitivity and Positive Predictive Value have been calculated based on the paper by Gardener & Giegerich, 2004.