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Table of contents:

  1. Overview

  2. Performance Plots

  3. Performance of RNAalifold(seed) - scored higher in this pairwise comparison

  4. Performance of TurboFold(20) - scored lower in this pairwise comparison

  5. Compile and download dataset for RNAalifold(seed) & TurboFold(20) [.zip] - may take several seconds...


Overview

Metric RNAalifold(seed) TurboFold(20)
MCC 0.701 > 0.653
Average MCC ± 95% Confidence Intervals 0.674 ± 0.125 > 0.668 ± 0.244
Sensitivity 0.538 < 0.606
Positive Predictive Value 0.922 > 0.714
Total TP 71 < 80
Total TN 9243 > 9208
Total FP 10 < 42
Total FP CONTRA 3 < 11
Total FP INCONS 3 < 21
Total FP COMP 4 < 10
Total FN 61 > 52
P-value 0.0

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Performance plots


  1. Comparison of performance of RNAalifold(seed) and TurboFold(20). Positive Predictive Value (PPV) is plotted against sensitivity. Each dot represents a single test of each method. See tables below for raw data (individual counts for RNAalifold(seed) and TurboFold(20)).

  2. Comparison of average Matthews Correlation Coefficients (MCCs) for RNAalifold(seed) and TurboFold(20). The whiskers correspond to 95% confidence intervals (CIs). 'n' denotes the number of MCCs used to calculate average MCCs and CIs. See tables below for raw data (individual counts for RNAalifold(seed) and TurboFold(20)).

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Performance of RNAalifold(seed) - scored higher in this pairwise comparison

1. Total counts & total scores for RNAalifold(seed)

Total Base Pair Counts
Total TP 71
Total TN 9243
Total FP 10
Total FP CONTRA 3
Total FP INCONS 3
Total FP COMP 4
Total FN 61
Total Scores
MCC 0.701
Average MCC ± 95% Confidence Intervals 0.674 ± 0.125
Sensitivity 0.538
Positive Predictive Value 0.922
Nr of predictions 6

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2. Individual counts for RNAalifold(seed) [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
3RKF_A 0.74 0.67 0.84 16 847 3 1 2 0 8
3SD1_A 0.70 0.59 0.85 17 1513 3 2 1 0 12
4A1C_2 0.50 0.25 1.00 5 4511 2 0 0 2 15
4AOB_A 0.85 0.72 1.00 21 1416 2 0 0 2 8
4ENB_A 0.63 0.40 1.00 6 466 0 0 0 0 9
4ENC_A 0.63 0.40 1.00 6 490 0 0 0 0 9

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Performance of TurboFold(20) - scored lower in this pairwise comparison

1. Total counts & total scores for TurboFold(20)

Total Base Pair Counts
Total TP 80
Total TN 9208
Total FP 42
Total FP CONTRA 11
Total FP INCONS 21
Total FP COMP 10
Total FN 52
Total Scores
MCC 0.653
Average MCC ± 95% Confidence Intervals 0.668 ± 0.244
Sensitivity 0.606
Positive Predictive Value 0.714
Nr of predictions 6

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2. Individual counts for TurboFold(20) [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
3RKF_A 0.91 0.83 1.00 20 846 0 0 0 0 4
3SD1_A 0.71 0.69 0.74 20 1506 7 2 5 0 9
4A1C_2 0.22 0.25 0.21 5 4492 28 6 13 9 15
4AOB_A 0.67 0.59 0.77 17 1415 6 2 3 1 12
4ENB_A 0.77 0.60 1.00 9 463 0 0 0 0 6
4ENC_A 0.73 0.60 0.90 9 486 1 1 0 0 6

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Matthews Correlation Coeffient, Sensitivity and Positive Predictive Value have been calculated based on the paper by Gardener & Giegerich, 2004.