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Table of contents:

  1. Overview

  2. Performance Plots

  3. Performance of RSpredict(20) - scored higher in this pairwise comparison

  4. Performance of PPfold(seed) - scored lower in this pairwise comparison

  5. Compile and download dataset for RSpredict(20) & PPfold(seed) [.zip] - may take several seconds...


Overview

Metric RSpredict(20) PPfold(seed)
MCC 0.573 > 0.036
Average MCC ± 95% Confidence Intervals 0.558 ± 0.276 > 0.016 ± 0.042
Sensitivity 0.530 > 0.008
Positive Predictive Value 0.631 > 0.200
Total TP 70 > 1
Total TN 9209 < 9315
Total FP 48 > 23
Total FP CONTRA 19 > 0
Total FP INCONS 22 > 4
Total FP COMP 7 < 19
Total FN 62 < 131
P-value 0.0

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Performance plots


  1. Comparison of performance of RSpredict(20) and PPfold(seed). Positive Predictive Value (PPV) is plotted against sensitivity. Each dot represents a single test of each method. See tables below for raw data (individual counts for RSpredict(20) and PPfold(seed)).

  2. Comparison of average Matthews Correlation Coefficients (MCCs) for RSpredict(20) and PPfold(seed). The whiskers correspond to 95% confidence intervals (CIs). 'n' denotes the number of MCCs used to calculate average MCCs and CIs. See tables below for raw data (individual counts for RSpredict(20) and PPfold(seed)).

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Performance of RSpredict(20) - scored higher in this pairwise comparison

1. Total counts & total scores for RSpredict(20)

Total Base Pair Counts
Total TP 70
Total TN 9209
Total FP 48
Total FP CONTRA 19
Total FP INCONS 22
Total FP COMP 7
Total FN 62
Total Scores
MCC 0.573
Average MCC ± 95% Confidence Intervals 0.558 ± 0.276
Sensitivity 0.530
Positive Predictive Value 0.631
Nr of predictions 6

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2. Individual counts for RSpredict(20) [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
3RKF_A 0.91 0.88 0.95 21 844 1 1 0 0 3
3SD1_A 0.82 0.86 0.78 25 1501 7 5 2 0 4
4A1C_2 0.25 0.30 0.21 6 4487 30 12 11 7 14
4AOB_A 0.33 0.21 0.55 6 1426 5 1 4 0 23
4ENB_A 0.54 0.40 0.75 6 464 2 0 2 0 9
4ENC_A 0.51 0.40 0.67 6 487 3 0 3 0 9

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Performance of PPfold(seed) - scored lower in this pairwise comparison

1. Total counts & total scores for PPfold(seed)

Total Base Pair Counts
Total TP 1
Total TN 9315
Total FP 23
Total FP CONTRA 0
Total FP INCONS 4
Total FP COMP 19
Total FN 131
Total Scores
MCC 0.036
Average MCC ± 95% Confidence Intervals 0.016 ± 0.042
Sensitivity 0.008
Positive Predictive Value 0.200
Nr of predictions 6

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2. Individual counts for PPfold(seed) [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
3RKF_A 0.00 0.00 0.00 0 866 0 0 0 0 24
3SD1_A 0.00 0.00 0.00 0 1533 0 0 0 0 29
4A1C_2 0.10 0.05 0.20 1 4511 23 0 4 19 19
4AOB_A 0.00 0.00 0.00 0 1437 0 0 0 0 29
4ENB_A 0.00 0.00 0.00 0 472 0 0 0 0 15
4ENC_A 0.00 0.00 0.00 0 496 0 0 0 0 15

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Matthews Correlation Coeffient, Sensitivity and Positive Predictive Value have been calculated based on the paper by Gardener & Giegerich, 2004.