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Table of contents:

  1. Overview

  2. Performance Plots

  3. Performance of TurboFold(20) - scored higher in this pairwise comparison

  4. Performance of Murlet(seed) - scored lower in this pairwise comparison

  5. Compile and download dataset for TurboFold(20) & Murlet(seed) [.zip] - may take several seconds...


Overview

Metric TurboFold(20) Murlet(seed)
MCC 0.653 > 0.621
Average MCC ± 95% Confidence Intervals 0.668 ± 0.244 > 0.620 ± 0.046
Sensitivity 0.606 > 0.424
Positive Predictive Value 0.714 < 0.918
Total TP 80 > 56
Total TN 9208 < 9259
Total FP 42 > 6
Total FP CONTRA 11 > 1
Total FP INCONS 21 > 4
Total FP COMP 10 > 1
Total FN 52 < 76
P-value 0.0

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Performance plots


  1. Comparison of performance of TurboFold(20) and Murlet(seed). Positive Predictive Value (PPV) is plotted against sensitivity. Each dot represents a single test of each method. See tables below for raw data (individual counts for TurboFold(20) and Murlet(seed)).

  2. Comparison of average Matthews Correlation Coefficients (MCCs) for TurboFold(20) and Murlet(seed). The whiskers correspond to 95% confidence intervals (CIs). 'n' denotes the number of MCCs used to calculate average MCCs and CIs. See tables below for raw data (individual counts for TurboFold(20) and Murlet(seed)).

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Performance of TurboFold(20) - scored higher in this pairwise comparison

1. Total counts & total scores for TurboFold(20)

Total Base Pair Counts
Total TP 80
Total TN 9208
Total FP 42
Total FP CONTRA 11
Total FP INCONS 21
Total FP COMP 10
Total FN 52
Total Scores
MCC 0.653
Average MCC ± 95% Confidence Intervals 0.668 ± 0.244
Sensitivity 0.606
Positive Predictive Value 0.714
Nr of predictions 6

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2. Individual counts for TurboFold(20) [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
3RKF_A 0.91 0.83 1.00 20 846 0 0 0 0 4
3SD1_A 0.71 0.69 0.74 20 1506 7 2 5 0 9
4A1C_2 0.22 0.25 0.21 5 4492 28 6 13 9 15
4AOB_A 0.67 0.59 0.77 17 1415 6 2 3 1 12
4ENB_A 0.77 0.60 1.00 9 463 0 0 0 0 6
4ENC_A 0.73 0.60 0.90 9 486 1 1 0 0 6

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Performance of Murlet(seed) - scored lower in this pairwise comparison

1. Total counts & total scores for Murlet(seed)

Total Base Pair Counts
Total TP 56
Total TN 9259
Total FP 6
Total FP CONTRA 1
Total FP INCONS 4
Total FP COMP 1
Total FN 76
Total Scores
MCC 0.621
Average MCC ± 95% Confidence Intervals 0.620 ± 0.046
Sensitivity 0.424
Positive Predictive Value 0.918
Nr of predictions 6

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2. Individual counts for Murlet(seed) [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
3RKF_A 0.62 0.50 0.80 12 851 3 1 2 0 12
3SD1_A 0.56 0.38 0.85 11 1520 2 0 2 0 18
4A1C_2 0.59 0.35 1.00 7 4509 0 0 0 0 13
4AOB_A 0.69 0.48 1.00 14 1423 1 0 0 1 15
4ENB_A 0.63 0.40 1.00 6 466 0 0 0 0 9
4ENC_A 0.63 0.40 1.00 6 490 0 0 0 0 9

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Matthews Correlation Coeffient, Sensitivity and Positive Predictive Value have been calculated based on the paper by Gardener & Giegerich, 2004.