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Table of contents:

  1. Overview

  2. Performance Plots

  3. Performance of TurboFold(20) - scored higher in this pairwise comparison

  4. Performance of RNASLOpt - scored lower in this pairwise comparison

  5. Compile and download dataset for TurboFold(20) & RNASLOpt [.zip] - may take several seconds...


Overview

Metric TurboFold(20) RNASLOpt
MCC 0.554 > 0.459
Average MCC ± 95% Confidence Intervals 0.598 ± 0.401 > 0.549 ± 0.451
Sensitivity 0.506 > 0.456
Positive Predictive Value 0.615 > 0.474
Total TP 40 > 36
Total TN 6856 > 6845
Total FP 35 < 49
Total FP CONTRA 9 < 17
Total FP INCONS 16 < 23
Total FP COMP 10 > 9
Total FN 39 < 43
P-value 0.0

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Performance plots


  1. Comparison of performance of TurboFold(20) and RNASLOpt. Positive Predictive Value (PPV) is plotted against sensitivity. Each dot represents a single test of each method. See tables below for raw data (individual counts for TurboFold(20) and RNASLOpt).

  2. Comparison of average Matthews Correlation Coefficients (MCCs) for TurboFold(20) and RNASLOpt. The whiskers correspond to 95% confidence intervals (CIs). 'n' denotes the number of MCCs used to calculate average MCCs and CIs. See tables below for raw data (individual counts for TurboFold(20) and RNASLOpt).

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Performance of TurboFold(20) - scored higher in this pairwise comparison

1. Total counts & total scores for TurboFold(20)

Total Base Pair Counts
Total TP 40
Total TN 6856
Total FP 35
Total FP CONTRA 9
Total FP INCONS 16
Total FP COMP 10
Total FN 39
Total Scores
MCC 0.554
Average MCC ± 95% Confidence Intervals 0.598 ± 0.401
Sensitivity 0.506
Positive Predictive Value 0.615
Nr of predictions 4

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2. Individual counts for TurboFold(20) [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
4A1C_2 0.22 0.25 0.21 5 4492 28 6 13 9 15
4AOB_A 0.67 0.59 0.77 17 1415 6 2 3 1 12
4ENB_A 0.77 0.60 1.00 9 463 0 0 0 0 6
4ENC_A 0.73 0.60 0.90 9 486 1 1 0 0 6

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Performance of RNASLOpt - scored lower in this pairwise comparison

1. Total counts & total scores for RNASLOpt

Total Base Pair Counts
Total TP 36
Total TN 6845
Total FP 49
Total FP CONTRA 17
Total FP INCONS 23
Total FP COMP 9
Total FN 43
Total Scores
MCC 0.459
Average MCC ± 95% Confidence Intervals 0.549 ± 0.451
Sensitivity 0.456
Positive Predictive Value 0.474
Nr of predictions 4

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2. Individual counts for RNASLOpt [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
4A1C_2 0.30 0.40 0.24 8 4482 35 13 13 9 12
4AOB_A 0.31 0.28 0.38 8 1416 13 3 10 0 21
4ENB_A 0.85 0.73 1.00 11 461 0 0 0 0 4
4ENC_A 0.73 0.60 0.90 9 486 1 1 0 0 6

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Matthews Correlation Coeffient, Sensitivity and Positive Predictive Value have been calculated based on the paper by Gardener & Giegerich, 2004.