CompaRNA - on-line benchmarks of RNA structure prediction methods

FAQ

Metric	TurboFold(20)		Sfold
MCC	0.653	>	0.636
Average MCC ± 95% Confidence Intervals	0.668 ± 0.244	>	0.654 ± 0.268
Sensitivity	0.606	>	0.598
Positive Predictive Value	0.714	>	0.687
Total TP	80	>	79
Total TN	9208	>	9205
Total FP	42	<	49
Total FP CONTRA	11	<	14
Total FP INCONS	21	<	22
Total FP COMP	10	<	13
Total FN	52	<	53
P-value	0.0

Comparison of performance of TurboFold(20) and Sfold. Positive Predictive Value (PPV) is plotted against sensitivity. Each dot represents a single test of each method. See tables below for raw data (individual counts for TurboFold(20) and Sfold).
Comparison of average Matthews Correlation Coefficients (MCCs) for TurboFold(20) and Sfold. The whiskers correspond to 95% confidence intervals (CIs). 'n' denotes the number of MCCs used to calculate average MCCs and CIs. See tables below for raw data (individual counts for TurboFold(20) and Sfold).

Total Scores
MCC	0.653
Average MCC ± 95% Confidence Intervals	0.668 ± 0.244
Sensitivity	0.606
Positive Predictive Value	0.714
Nr of predictions	6

RNA Chain	Rfam family	MCC	SENS	PPV	TP	TN	FP	FP CONTRA	FP INCONS	FP COMP	FN
3RKF_A	Purine links to Rfam database...	0.91	0.83	1.00	20	846	0	0	0	0	4
3SD1_A	THF links to Rfam database...	0.71	0.69	0.74	20	1506	7	2	5	0	9
4A1C_2	5_8S_rRNA links to Rfam database...	0.22	0.25	0.21	5	4492	28	6	13	9	15
4AOB_A	SAM links to Rfam database...	0.67	0.59	0.77	17	1415	6	2	3	1	12
4ENB_A	crcB links to Rfam database...	0.77	0.60	1.00	9	463	0	0	0	0	6
4ENC_A	crcB links to Rfam database...	0.73	0.60	0.90	9	486	1	1	0	0	6

Total Scores
MCC	0.636
Average MCC ± 95% Confidence Intervals	0.654 ± 0.268
Sensitivity	0.598
Positive Predictive Value	0.687
Nr of predictions	6

RNA Chain	Rfam family	MCC	SENS	PPV	TP	TN	FP	FP CONTRA	FP INCONS	FP COMP	FN
3RKF_A	Purine links to Rfam database...	0.91	0.83	1.00	20	846	0	0	0	0	4
3SD1_A	THF links to Rfam database...	0.78	0.72	0.84	21	1508	4	2	2	0	8
4A1C_2	5_8S_rRNA links to Rfam database...	0.21	0.25	0.19	5	4489	34	8	14	12	15
4AOB_A	SAM links to Rfam database...	0.60	0.59	0.63	17	1410	11	4	6	1	12
4ENB_A	crcB links to Rfam database...	0.85	0.73	1.00	11	461	0	0	0	0	4
4ENC_A	crcB links to Rfam database...	0.57	0.33	1.00	5	491	0	0	0	0	10

Matthews Correlation Coeffient, Sensitivity and Positive Predictive Value have been calculated based on the paper by Gardener & Giegerich, 2004.