CompaRNA - on-line benchmarks of RNA structure prediction methods
Home

Methods
Datasets
Rankings
RNA 2D Atlas

Help
FAQ

Contact us
RSS feeds
Twitter

Table of contents:

  1. Overview

  2. Performance Plots

  3. Performance of TurboFold(20) - scored higher in this pairwise comparison

  4. Performance of Vsfold5 - scored lower in this pairwise comparison

  5. Compile and download dataset for TurboFold(20) & Vsfold5 [.zip] - may take several seconds...


Overview

Metric TurboFold(20) Vsfold5
MCC 0.653 > 0.518
Average MCC ± 95% Confidence Intervals 0.668 ± 0.244 > 0.589 ± 0.426
Sensitivity 0.606 > 0.530
Positive Predictive Value 0.714 > 0.519
Total TP 80 > 70
Total TN 9208 > 9185
Total FP 42 < 82
Total FP CONTRA 11 < 19
Total FP INCONS 21 < 46
Total FP COMP 10 < 17
Total FN 52 < 62
P-value 0.0

^top




Performance plots


  1. Comparison of performance of TurboFold(20) and Vsfold5. Positive Predictive Value (PPV) is plotted against sensitivity. Each dot represents a single test of each method. See tables below for raw data (individual counts for TurboFold(20) and Vsfold5).

  2. Comparison of average Matthews Correlation Coefficients (MCCs) for TurboFold(20) and Vsfold5. The whiskers correspond to 95% confidence intervals (CIs). 'n' denotes the number of MCCs used to calculate average MCCs and CIs. See tables below for raw data (individual counts for TurboFold(20) and Vsfold5).

^top





Performance of TurboFold(20) - scored higher in this pairwise comparison

1. Total counts & total scores for TurboFold(20)

Total Base Pair Counts
Total TP 80
Total TN 9208
Total FP 42
Total FP CONTRA 11
Total FP INCONS 21
Total FP COMP 10
Total FN 52
Total Scores
MCC 0.653
Average MCC ± 95% Confidence Intervals 0.668 ± 0.244
Sensitivity 0.606
Positive Predictive Value 0.714
Nr of predictions 6

^top



2. Individual counts for TurboFold(20) [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
3RKF_A 0.91 0.83 1.00 20 846 0 0 0 0 4
3SD1_A 0.71 0.69 0.74 20 1506 7 2 5 0 9
4A1C_2 0.22 0.25 0.21 5 4492 28 6 13 9 15
4AOB_A 0.67 0.59 0.77 17 1415 6 2 3 1 12
4ENB_A 0.77 0.60 1.00 9 463 0 0 0 0 6
4ENC_A 0.73 0.60 0.90 9 486 1 1 0 0 6

^top



Performance of Vsfold5 - scored lower in this pairwise comparison

1. Total counts & total scores for Vsfold5

Total Base Pair Counts
Total TP 70
Total TN 9185
Total FP 82
Total FP CONTRA 19
Total FP INCONS 46
Total FP COMP 17
Total FN 62
Total Scores
MCC 0.518
Average MCC ± 95% Confidence Intervals 0.589 ± 0.426
Sensitivity 0.530
Positive Predictive Value 0.519
Nr of predictions 6

^top



2. Individual counts for Vsfold5 [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
3RKF_A 0.90 0.92 0.88 22 841 3 3 0 0 2
3SD1_A 0.13 0.14 0.15 4 1507 22 5 17 0 25
4A1C_2 0.33 0.40 0.28 8 4487 37 8 13 16 12
4AOB_A 0.21 0.21 0.25 6 1413 19 2 16 1 23
4ENB_A 1.00 1.00 1.00 15 457 0 0 0 0 0
4ENC_A 0.97 1.00 0.94 15 480 1 1 0 0 0

^top


Matthews Correlation Coeffient, Sensitivity and Positive Predictive Value have been calculated based on the paper by Gardener & Giegerich, 2004.