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Table of contents:

  1. Overview

  2. Performance Plots

  3. Performance of TurboFold(seed) - scored higher in this pairwise comparison

  4. Performance of Mastr(20) - scored lower in this pairwise comparison

  5. Compile and download dataset for TurboFold(seed) & Mastr(20) [.zip] - may take several seconds...


Overview

Metric TurboFold(seed) Mastr(20)
MCC 0.636 > 0.570
Average MCC ± 95% Confidence Intervals 0.664 ± 0.254 > 0.500 ± 0.309
Sensitivity 0.606 > 0.424
Positive Predictive Value 0.678 < 0.778
Total TP 80 > 56
Total TN 9202 < 9248
Total FP 51 > 17
Total FP CONTRA 14 > 5
Total FP INCONS 24 > 11
Total FP COMP 13 > 1
Total FN 52 < 76
P-value 0.0

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Performance plots


  1. Comparison of performance of TurboFold(seed) and Mastr(20). Positive Predictive Value (PPV) is plotted against sensitivity. Each dot represents a single test of each method. See tables below for raw data (individual counts for TurboFold(seed) and Mastr(20)).

  2. Comparison of average Matthews Correlation Coefficients (MCCs) for TurboFold(seed) and Mastr(20). The whiskers correspond to 95% confidence intervals (CIs). 'n' denotes the number of MCCs used to calculate average MCCs and CIs. See tables below for raw data (individual counts for TurboFold(seed) and Mastr(20)).

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Performance of TurboFold(seed) - scored higher in this pairwise comparison

1. Total counts & total scores for TurboFold(seed)

Total Base Pair Counts
Total TP 80
Total TN 9202
Total FP 51
Total FP CONTRA 14
Total FP INCONS 24
Total FP COMP 13
Total FN 52
Total Scores
MCC 0.636
Average MCC ± 95% Confidence Intervals 0.664 ± 0.254
Sensitivity 0.606
Positive Predictive Value 0.678
Nr of predictions 6

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2. Individual counts for TurboFold(seed) [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
3RKF_A 0.91 0.83 1.00 20 846 0 0 0 0 4
3SD1_A 0.71 0.69 0.74 20 1506 7 2 5 0 9
4A1C_2 0.20 0.25 0.17 5 4486 37 9 16 12 15
4AOB_A 0.67 0.59 0.77 17 1415 6 2 3 1 12
4ENB_A 0.77 0.60 1.00 9 463 0 0 0 0 6
4ENC_A 0.73 0.60 0.90 9 486 1 1 0 0 6

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Performance of Mastr(20) - scored lower in this pairwise comparison

1. Total counts & total scores for Mastr(20)

Total Base Pair Counts
Total TP 56
Total TN 9248
Total FP 17
Total FP CONTRA 5
Total FP INCONS 11
Total FP COMP 1
Total FN 76
Total Scores
MCC 0.570
Average MCC ± 95% Confidence Intervals 0.500 ± 0.309
Sensitivity 0.424
Positive Predictive Value 0.778
Nr of predictions 6

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2. Individual counts for Mastr(20) [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
3RKF_A 0.84 0.71 1.00 17 849 0 0 0 0 7
3SD1_A 0.73 0.72 0.75 21 1505 7 4 3 0 8
4A1C_2 0.00 0.00 0.00 0 4516 0 0 0 0 20
4AOB_A 0.42 0.34 0.53 10 1418 10 1 8 1 19
4ENB_A 0.44 0.20 1.00 3 469 0 0 0 0 12
4ENC_A 0.57 0.33 1.00 5 491 0 0 0 0 10

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Matthews Correlation Coeffient, Sensitivity and Positive Predictive Value have been calculated based on the paper by Gardener & Giegerich, 2004.