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Table of contents:

  1. Overview

  2. Performance Plots

  3. Performance of TurboFold(seed) - scored higher in this pairwise comparison

  4. Performance of RSpredict(20) - scored lower in this pairwise comparison

  5. Compile and download dataset for TurboFold(seed) & RSpredict(20) [.zip] - may take several seconds...


Overview

Metric TurboFold(seed) RSpredict(20)
MCC 0.636 > 0.573
Average MCC ± 95% Confidence Intervals 0.664 ± 0.254 > 0.558 ± 0.276
Sensitivity 0.606 > 0.530
Positive Predictive Value 0.678 > 0.631
Total TP 80 > 70
Total TN 9202 < 9209
Total FP 51 > 48
Total FP CONTRA 14 < 19
Total FP INCONS 24 > 22
Total FP COMP 13 > 7
Total FN 52 < 62
P-value 0.0

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Performance plots


  1. Comparison of performance of TurboFold(seed) and RSpredict(20). Positive Predictive Value (PPV) is plotted against sensitivity. Each dot represents a single test of each method. See tables below for raw data (individual counts for TurboFold(seed) and RSpredict(20)).

  2. Comparison of average Matthews Correlation Coefficients (MCCs) for TurboFold(seed) and RSpredict(20). The whiskers correspond to 95% confidence intervals (CIs). 'n' denotes the number of MCCs used to calculate average MCCs and CIs. See tables below for raw data (individual counts for TurboFold(seed) and RSpredict(20)).

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Performance of TurboFold(seed) - scored higher in this pairwise comparison

1. Total counts & total scores for TurboFold(seed)

Total Base Pair Counts
Total TP 80
Total TN 9202
Total FP 51
Total FP CONTRA 14
Total FP INCONS 24
Total FP COMP 13
Total FN 52
Total Scores
MCC 0.636
Average MCC ± 95% Confidence Intervals 0.664 ± 0.254
Sensitivity 0.606
Positive Predictive Value 0.678
Nr of predictions 6

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2. Individual counts for TurboFold(seed) [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
3RKF_A 0.91 0.83 1.00 20 846 0 0 0 0 4
3SD1_A 0.71 0.69 0.74 20 1506 7 2 5 0 9
4A1C_2 0.20 0.25 0.17 5 4486 37 9 16 12 15
4AOB_A 0.67 0.59 0.77 17 1415 6 2 3 1 12
4ENB_A 0.77 0.60 1.00 9 463 0 0 0 0 6
4ENC_A 0.73 0.60 0.90 9 486 1 1 0 0 6

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Performance of RSpredict(20) - scored lower in this pairwise comparison

1. Total counts & total scores for RSpredict(20)

Total Base Pair Counts
Total TP 70
Total TN 9209
Total FP 48
Total FP CONTRA 19
Total FP INCONS 22
Total FP COMP 7
Total FN 62
Total Scores
MCC 0.573
Average MCC ± 95% Confidence Intervals 0.558 ± 0.276
Sensitivity 0.530
Positive Predictive Value 0.631
Nr of predictions 6

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2. Individual counts for RSpredict(20) [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
3RKF_A 0.91 0.88 0.95 21 844 1 1 0 0 3
3SD1_A 0.82 0.86 0.78 25 1501 7 5 2 0 4
4A1C_2 0.25 0.30 0.21 6 4487 30 12 11 7 14
4AOB_A 0.33 0.21 0.55 6 1426 5 1 4 0 23
4ENB_A 0.54 0.40 0.75 6 464 2 0 2 0 9
4ENC_A 0.51 0.40 0.67 6 487 3 0 3 0 9

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Matthews Correlation Coeffient, Sensitivity and Positive Predictive Value have been calculated based on the paper by Gardener & Giegerich, 2004.