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Table of contents:

  1. Overview

  2. Performance Plots

  3. Performance of ContextFold - scored higher in this pairwise comparison

  4. Performance of MXScarna(20) - scored lower in this pairwise comparison

  5. Compile and download dataset for ContextFold & MXScarna(20) [.zip] - may take several seconds...


Overview

Metric ContextFold MXScarna(20)
MCC 0.579 > 0.501
Average MCC ± 95% Confidence Intervals 0.568 ± 0.278 > 0.462 ± 0.279
Sensitivity 0.443 > 0.401
Positive Predictive Value 0.763 > 0.632
Total TP 74 > 67
Total TN 25796 > 25787
Total FP 37 < 58
Total FP CONTRA 2 < 4
Total FP INCONS 21 < 35
Total FP COMP 14 < 19
Total FN 93 < 100
P-value 0.0

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Performance plots


  1. Comparison of performance of ContextFold and MXScarna(20). Positive Predictive Value (PPV) is plotted against sensitivity. Each dot represents a single test of each method. See tables below for raw data (individual counts for ContextFold and MXScarna(20)).

  2. Comparison of average Matthews Correlation Coefficients (MCCs) for ContextFold and MXScarna(20). The whiskers correspond to 95% confidence intervals (CIs). 'n' denotes the number of MCCs used to calculate average MCCs and CIs. See tables below for raw data (individual counts for ContextFold and MXScarna(20)).

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Performance of ContextFold - scored higher in this pairwise comparison

1. Total counts & total scores for ContextFold

Total Base Pair Counts
Total TP 74
Total TN 25796
Total FP 37
Total FP CONTRA 2
Total FP INCONS 21
Total FP COMP 14
Total FN 93
Total Scores
MCC 0.579
Average MCC ± 95% Confidence Intervals 0.568 ± 0.278
Sensitivity 0.443
Positive Predictive Value 0.763
Nr of predictions 5

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2. Individual counts for ContextFold [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
4A1C_3 0.78 0.63 0.97 34 7105 1 0 1 0 20
4A1C_2 0.20 0.15 0.28 5 11763 26 0 13 13 28
4AOB_A 0.52 0.40 0.68 17 4346 9 1 7 1 25
4ENB_A 0.69 0.47 1.00 9 1266 0 0 0 0 10
4ENC_A 0.65 0.47 0.90 9 1316 1 1 0 0 10

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Performance of MXScarna(20) - scored lower in this pairwise comparison

1. Total counts & total scores for MXScarna(20)

Total Base Pair Counts
Total TP 67
Total TN 25787
Total FP 58
Total FP CONTRA 4
Total FP INCONS 35
Total FP COMP 19
Total FN 100
Total Scores
MCC 0.501
Average MCC ± 95% Confidence Intervals 0.462 ± 0.279
Sensitivity 0.401
Positive Predictive Value 0.632
Nr of predictions 5

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2. Individual counts for MXScarna(20) [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
4A1C_3 0.64 0.56 0.75 30 7100 11 2 8 1 24
4A1C_2 0.18 0.15 0.21 5 11757 36 2 17 17 28
4AOB_A 0.62 0.55 0.72 23 4339 10 0 9 1 19
4ENB_A 0.26 0.11 0.67 2 1272 1 0 1 0 17
4ENC_A 0.60 0.37 1.00 7 1319 0 0 0 0 12

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Matthews Correlation Coeffient, Sensitivity and Positive Predictive Value have been calculated based on the paper by Gardener & Giegerich, 2004.