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Table of contents:

  1. Overview

  2. Performance Plots

  3. Performance of ContextFold - scored higher in this pairwise comparison

  4. Performance of Murlet(seed) - scored lower in this pairwise comparison

  5. Compile and download dataset for ContextFold & Murlet(seed) [.zip] - may take several seconds...


Overview

Metric ContextFold Murlet(seed)
MCC 0.488 > 0.425
Average MCC ± 95% Confidence Intervals 0.523 ± 0.237 > 0.429 ± 0.310
Sensitivity 0.376 > 0.248
Positive Predictive Value 0.641 < 0.733
Total TP 50 > 33
Total TN 20215 < 20248
Total FP 42 > 13
Total FP CONTRA 2 > 0
Total FP INCONS 26 > 12
Total FP COMP 14 > 1
Total FN 83 < 100
P-value 0.0

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Performance plots


  1. Comparison of performance of ContextFold and Murlet(seed). Positive Predictive Value (PPV) is plotted against sensitivity. Each dot represents a single test of each method. See tables below for raw data (individual counts for ContextFold and Murlet(seed)).

  2. Comparison of average Matthews Correlation Coefficients (MCCs) for ContextFold and Murlet(seed). The whiskers correspond to 95% confidence intervals (CIs). 'n' denotes the number of MCCs used to calculate average MCCs and CIs. See tables below for raw data (individual counts for ContextFold and Murlet(seed)).

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Performance of ContextFold - scored higher in this pairwise comparison

1. Total counts & total scores for ContextFold

Total Base Pair Counts
Total TP 50
Total TN 20215
Total FP 42
Total FP CONTRA 2
Total FP INCONS 26
Total FP COMP 14
Total FN 83
Total Scores
MCC 0.488
Average MCC ± 95% Confidence Intervals 0.523 ± 0.237
Sensitivity 0.376
Positive Predictive Value 0.641
Nr of predictions 5

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2. Individual counts for ContextFold [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
2LC8_A 0.55 0.50 0.63 10 1524 6 0 6 0 10
4A1C_2 0.20 0.15 0.28 5 11763 26 0 13 13 28
4AOB_A 0.52 0.40 0.68 17 4346 9 1 7 1 25
4ENB_A 0.69 0.47 1.00 9 1266 0 0 0 0 10
4ENC_A 0.65 0.47 0.90 9 1316 1 1 0 0 10

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Performance of Murlet(seed) - scored lower in this pairwise comparison

1. Total counts & total scores for Murlet(seed)

Total Base Pair Counts
Total TP 33
Total TN 20248
Total FP 13
Total FP CONTRA 0
Total FP INCONS 12
Total FP COMP 1
Total FN 100
Total Scores
MCC 0.425
Average MCC ± 95% Confidence Intervals 0.429 ± 0.310
Sensitivity 0.248
Positive Predictive Value 0.733
Nr of predictions 5

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2. Individual counts for Murlet(seed) [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
2LC8_A -0.01 0.00 0.00 0 1528 12 0 12 0 20
4A1C_2 0.46 0.21 1.00 7 11774 0 0 0 0 26
4AOB_A 0.58 0.33 1.00 14 4357 1 0 0 1 28
4ENB_A 0.56 0.32 1.00 6 1269 0 0 0 0 13
4ENC_A 0.56 0.32 1.00 6 1320 0 0 0 0 13

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Matthews Correlation Coeffient, Sensitivity and Positive Predictive Value have been calculated based on the paper by Gardener & Giegerich, 2004.