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Table of contents:

  1. Overview

  2. Performance Plots

  3. Performance of ContextFold - scored higher in this pairwise comparison

  4. Performance of RNASampler(seed) - scored lower in this pairwise comparison

  5. Compile and download dataset for ContextFold & RNASampler(seed) [.zip] - may take several seconds...


Overview

Metric ContextFold RNASampler(seed)
MCC 0.351 > 0.198
Average MCC ± 95% Confidence Intervals 0.379 ± 2.226 > 0.150 ± 2.027
Sensitivity 0.283 > 0.151
Positive Predictive Value 0.441 > 0.267
Total TP 15 > 8
Total TN 13287 < 13291
Total FP 32 > 30
Total FP CONTRA 0 = 0
Total FP INCONS 19 < 22
Total FP COMP 13 > 8
Total FN 38 < 45
P-value 0.0

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Performance plots


  1. Comparison of performance of ContextFold and RNASampler(seed). Positive Predictive Value (PPV) is plotted against sensitivity. Each dot represents a single test of each method. See tables below for raw data (individual counts for ContextFold and RNASampler(seed)).

  2. Comparison of average Matthews Correlation Coefficients (MCCs) for ContextFold and RNASampler(seed). The whiskers correspond to 95% confidence intervals (CIs). 'n' denotes the number of MCCs used to calculate average MCCs and CIs. See tables below for raw data (individual counts for ContextFold and RNASampler(seed)).

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Performance of ContextFold - scored higher in this pairwise comparison

1. Total counts & total scores for ContextFold

Total Base Pair Counts
Total TP 15
Total TN 13287
Total FP 32
Total FP CONTRA 0
Total FP INCONS 19
Total FP COMP 13
Total FN 38
Total Scores
MCC 0.351
Average MCC ± 95% Confidence Intervals 0.379 ± 2.226
Sensitivity 0.283
Positive Predictive Value 0.441
Nr of predictions 2

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2. Individual counts for ContextFold [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
2LC8_A 0.55 0.50 0.63 10 1524 6 0 6 0 10
4A1C_2 0.20 0.15 0.28 5 11763 26 0 13 13 28

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Performance of RNASampler(seed) - scored lower in this pairwise comparison

1. Total counts & total scores for RNASampler(seed)

Total Base Pair Counts
Total TP 8
Total TN 13291
Total FP 30
Total FP CONTRA 0
Total FP INCONS 22
Total FP COMP 8
Total FN 45
Total Scores
MCC 0.198
Average MCC ± 95% Confidence Intervals 0.150 ± 2.027
Sensitivity 0.151
Positive Predictive Value 0.267
Nr of predictions 2

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2. Individual counts for RNASampler(seed) [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
2LC8_A -0.01 0.00 0.00 0 1530 10 0 10 0 20
4A1C_2 0.31 0.24 0.40 8 11761 20 0 12 8 25

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Matthews Correlation Coeffient, Sensitivity and Positive Predictive Value have been calculated based on the paper by Gardener & Giegerich, 2004.