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Table of contents:

  1. Overview

  2. Performance Plots

  3. Performance of ContextFold - scored higher in this pairwise comparison

  4. Performance of TurboFold(seed) - scored lower in this pairwise comparison

  5. Compile and download dataset for ContextFold & TurboFold(seed) [.zip] - may take several seconds...


Overview

Metric ContextFold TurboFold(seed)
MCC 0.576 > 0.460
Average MCC ± 95% Confidence Intervals 0.566 ± 0.210 > 0.454 ± 0.321
Sensitivity 0.449 > 0.380
Positive Predictive Value 0.743 > 0.563
Total TP 84 > 71
Total TN 27320 > 27307
Total FP 43 < 65
Total FP CONTRA 2 < 7
Total FP INCONS 27 < 48
Total FP COMP 14 > 10
Total FN 103 < 116
P-value 0.0

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Performance plots


  1. Comparison of performance of ContextFold and TurboFold(seed). Positive Predictive Value (PPV) is plotted against sensitivity. Each dot represents a single test of each method. See tables below for raw data (individual counts for ContextFold and TurboFold(seed)).

  2. Comparison of average Matthews Correlation Coefficients (MCCs) for ContextFold and TurboFold(seed). The whiskers correspond to 95% confidence intervals (CIs). 'n' denotes the number of MCCs used to calculate average MCCs and CIs. See tables below for raw data (individual counts for ContextFold and TurboFold(seed)).

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Performance of ContextFold - scored higher in this pairwise comparison

1. Total counts & total scores for ContextFold

Total Base Pair Counts
Total TP 84
Total TN 27320
Total FP 43
Total FP CONTRA 2
Total FP INCONS 27
Total FP COMP 14
Total FN 103
Total Scores
MCC 0.576
Average MCC ± 95% Confidence Intervals 0.566 ± 0.210
Sensitivity 0.449
Positive Predictive Value 0.743
Nr of predictions 6

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2. Individual counts for ContextFold [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
2LC8_A 0.55 0.50 0.63 10 1524 6 0 6 0 10
4A1C_3 0.78 0.63 0.97 34 7105 1 0 1 0 20
4A1C_2 0.20 0.15 0.28 5 11763 26 0 13 13 28
4AOB_A 0.52 0.40 0.68 17 4346 9 1 7 1 25
4ENB_A 0.69 0.47 1.00 9 1266 0 0 0 0 10
4ENC_A 0.65 0.47 0.90 9 1316 1 1 0 0 10

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Performance of TurboFold(seed) - scored lower in this pairwise comparison

1. Total counts & total scores for TurboFold(seed)

Total Base Pair Counts
Total TP 71
Total TN 27307
Total FP 65
Total FP CONTRA 7
Total FP INCONS 48
Total FP COMP 10
Total FN 116
Total Scores
MCC 0.460
Average MCC ± 95% Confidence Intervals 0.454 ± 0.321
Sensitivity 0.380
Positive Predictive Value 0.563
Nr of predictions 6

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2. Individual counts for TurboFold(seed) [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
2LC8_A -0.01 0.00 0.00 0 1525 15 2 13 0 20
4A1C_3 0.69 0.57 0.84 31 7103 6 0 6 0 23
4A1C_2 0.15 0.15 0.15 5 11748 37 3 25 9 28
4AOB_A 0.56 0.40 0.77 17 4349 6 1 4 1 25
4ENB_A 0.69 0.47 1.00 9 1266 0 0 0 0 10
4ENC_A 0.65 0.47 0.90 9 1316 1 1 0 0 10

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Matthews Correlation Coeffient, Sensitivity and Positive Predictive Value have been calculated based on the paper by Gardener & Giegerich, 2004.