CompaRNA - on-line benchmarks of RNA structure prediction methods

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Metric	MXScarna(20)		Multilign(seed)
MCC	0.652	>	0.631
Average MCC ± 95% Confidence Intervals	0.661 ± 0.138	>	0.641 ± 0.275
Sensitivity	0.542	>	0.492
Positive Predictive Value	0.790	<	0.817
Total TP	64	>	58
Total TN	10417	<	10427
Total FP	18	>	14
Total FP CONTRA	2	>	1
Total FP INCONS	15	>	12
Total FP COMP	1	=	1
Total FN	54	<	60
P-value	0.0

Comparison of performance of MXScarna(20) and Multilign(seed). Positive Predictive Value (PPV) is plotted against sensitivity. Each dot represents a single test of each method. See tables below for raw data (individual counts for MXScarna(20) and Multilign(seed)).
Comparison of average Matthews Correlation Coefficients (MCCs) for MXScarna(20) and Multilign(seed). The whiskers correspond to 95% confidence intervals (CIs). 'n' denotes the number of MCCs used to calculate average MCCs and CIs. See tables below for raw data (individual counts for MXScarna(20) and Multilign(seed)).

Total Scores
MCC	0.652
Average MCC ± 95% Confidence Intervals	0.661 ± 0.138
Sensitivity	0.542
Positive Predictive Value	0.790
Nr of predictions	3

RNA Chain	Rfam family	MCC	SENS	PPV	TP	TN	FP	FP CONTRA	FP INCONS	FP COMP	FN
3RKF_A	Purine links to Rfam database...	0.72	0.53	1.00	18	2193	0	0	0	0	16
3SD1_A	THF links to Rfam database...	0.63	0.55	0.74	23	3885	8	2	6	0	19
4AOB_A	SAM links to Rfam database...	0.62	0.55	0.72	23	4339	10	0	9	1	19

Total Scores
MCC	0.631
Average MCC ± 95% Confidence Intervals	0.641 ± 0.275
Sensitivity	0.492
Positive Predictive Value	0.817
Nr of predictions	3

RNA Chain	Rfam family	MCC	SENS	PPV	TP	TN	FP	FP CONTRA	FP INCONS	FP COMP	FN
3RKF_A	Purine links to Rfam database...	0.76	0.59	1.00	20	2191	0	0	0	0	14
3SD1_A	THF links to Rfam database...	0.55	0.45	0.68	19	3888	9	1	8	0	23
4AOB_A	SAM links to Rfam database...	0.61	0.45	0.83	19	4348	5	0	4	1	23

Matthews Correlation Coeffient, Sensitivity and Positive Predictive Value have been calculated based on the paper by Gardener & Giegerich, 2004.