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Table of contents:

  1. Overview

  2. Performance Plots

  3. Performance of MXScarna(20) - scored higher in this pairwise comparison

  4. Performance of RNASLOpt - scored lower in this pairwise comparison

  5. Compile and download dataset for MXScarna(20) & RNASLOpt [.zip] - may take several seconds...


Overview

Metric MXScarna(20) RNASLOpt
MCC 0.501 > 0.467
Average MCC ± 95% Confidence Intervals 0.462 ± 0.279 < 0.514 ± 0.309
Sensitivity 0.401 > 0.383
Positive Predictive Value 0.632 > 0.577
Total TP 67 > 64
Total TN 25787 > 25782
Total FP 58 > 53
Total FP CONTRA 4 < 11
Total FP INCONS 35 < 36
Total FP COMP 19 > 6
Total FN 100 < 103
P-value 0.0

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Performance plots


  1. Comparison of performance of MXScarna(20) and RNASLOpt. Positive Predictive Value (PPV) is plotted against sensitivity. Each dot represents a single test of each method. See tables below for raw data (individual counts for MXScarna(20) and RNASLOpt).

  2. Comparison of average Matthews Correlation Coefficients (MCCs) for MXScarna(20) and RNASLOpt. The whiskers correspond to 95% confidence intervals (CIs). 'n' denotes the number of MCCs used to calculate average MCCs and CIs. See tables below for raw data (individual counts for MXScarna(20) and RNASLOpt).

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Performance of MXScarna(20) - scored higher in this pairwise comparison

1. Total counts & total scores for MXScarna(20)

Total Base Pair Counts
Total TP 67
Total TN 25787
Total FP 58
Total FP CONTRA 4
Total FP INCONS 35
Total FP COMP 19
Total FN 100
Total Scores
MCC 0.501
Average MCC ± 95% Confidence Intervals 0.462 ± 0.279
Sensitivity 0.401
Positive Predictive Value 0.632
Nr of predictions 5

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2. Individual counts for MXScarna(20) [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
4A1C_3 0.64 0.56 0.75 30 7100 11 2 8 1 24
4A1C_2 0.18 0.15 0.21 5 11757 36 2 17 17 28
4AOB_A 0.62 0.55 0.72 23 4339 10 0 9 1 19
4ENB_A 0.26 0.11 0.67 2 1272 1 0 1 0 17
4ENC_A 0.60 0.37 1.00 7 1319 0 0 0 0 12

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Performance of RNASLOpt - scored lower in this pairwise comparison

1. Total counts & total scores for RNASLOpt

Total Base Pair Counts
Total TP 64
Total TN 25782
Total FP 53
Total FP CONTRA 11
Total FP INCONS 36
Total FP COMP 6
Total FN 103
Total Scores
MCC 0.467
Average MCC ± 95% Confidence Intervals 0.514 ± 0.309
Sensitivity 0.383
Positive Predictive Value 0.577
Nr of predictions 5

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2. Individual counts for RNASLOpt [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
4A1C_3 0.67 0.52 0.88 28 7108 4 0 4 0 26
4A1C_2 0.23 0.24 0.22 8 11744 35 8 21 6 25
4AOB_A 0.26 0.19 0.38 8 4350 13 2 11 0 34
4ENB_A 0.76 0.58 1.00 11 1264 0 0 0 0 8
4ENC_A 0.65 0.47 0.90 9 1316 1 1 0 0 10

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Matthews Correlation Coeffient, Sensitivity and Positive Predictive Value have been calculated based on the paper by Gardener & Giegerich, 2004.