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Table of contents:

  1. Overview

  2. Performance Plots

  3. Performance of Mastr(20) - scored higher in this pairwise comparison

  4. Performance of RNASLOpt - scored lower in this pairwise comparison

  5. Compile and download dataset for Mastr(20) & RNASLOpt [.zip] - may take several seconds...


Overview

Metric Mastr(20) RNASLOpt
MCC 0.488 > 0.467
Average MCC ± 95% Confidence Intervals 0.399 ± 0.320 < 0.514 ± 0.309
Sensitivity 0.305 < 0.383
Positive Predictive Value 0.785 > 0.577
Total TP 51 < 64
Total TN 25828 > 25782
Total FP 16 < 53
Total FP CONTRA 0 < 11
Total FP INCONS 14 < 36
Total FP COMP 2 < 6
Total FN 116 > 103
P-value 0.0

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Performance plots


  1. Comparison of performance of Mastr(20) and RNASLOpt. Positive Predictive Value (PPV) is plotted against sensitivity. Each dot represents a single test of each method. See tables below for raw data (individual counts for Mastr(20) and RNASLOpt).

  2. Comparison of average Matthews Correlation Coefficients (MCCs) for Mastr(20) and RNASLOpt. The whiskers correspond to 95% confidence intervals (CIs). 'n' denotes the number of MCCs used to calculate average MCCs and CIs. See tables below for raw data (individual counts for Mastr(20) and RNASLOpt).

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Performance of Mastr(20) - scored higher in this pairwise comparison

1. Total counts & total scores for Mastr(20)

Total Base Pair Counts
Total TP 51
Total TN 25828
Total FP 16
Total FP CONTRA 0
Total FP INCONS 14
Total FP COMP 2
Total FN 116
Total Scores
MCC 0.488
Average MCC ± 95% Confidence Intervals 0.399 ± 0.320
Sensitivity 0.305
Positive Predictive Value 0.785
Nr of predictions 5

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2. Individual counts for Mastr(20) [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
4A1C_3 0.70 0.59 0.84 32 7102 7 0 6 1 22
4A1C_2 0.00 0.00 0.00 0 11781 0 0 0 0 33
4AOB_A 0.39 0.26 0.58 11 4352 9 0 8 1 31
4ENB_A 0.39 0.16 1.00 3 1272 0 0 0 0 16
4ENC_A 0.51 0.26 1.00 5 1321 0 0 0 0 14

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Performance of RNASLOpt - scored lower in this pairwise comparison

1. Total counts & total scores for RNASLOpt

Total Base Pair Counts
Total TP 64
Total TN 25782
Total FP 53
Total FP CONTRA 11
Total FP INCONS 36
Total FP COMP 6
Total FN 103
Total Scores
MCC 0.467
Average MCC ± 95% Confidence Intervals 0.514 ± 0.309
Sensitivity 0.383
Positive Predictive Value 0.577
Nr of predictions 5

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2. Individual counts for RNASLOpt [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
4A1C_3 0.67 0.52 0.88 28 7108 4 0 4 0 26
4A1C_2 0.23 0.24 0.22 8 11744 35 8 21 6 25
4AOB_A 0.26 0.19 0.38 8 4350 13 2 11 0 34
4ENB_A 0.76 0.58 1.00 11 1264 0 0 0 0 8
4ENC_A 0.65 0.47 0.90 9 1316 1 1 0 0 10

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Matthews Correlation Coeffient, Sensitivity and Positive Predictive Value have been calculated based on the paper by Gardener & Giegerich, 2004.