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Table of contents:

  1. Overview

  2. Performance Plots

  3. Performance of Multilign(20) - scored higher in this pairwise comparison

  4. Performance of Mastr(seed) - scored lower in this pairwise comparison

  5. Compile and download dataset for Multilign(20) & Mastr(seed) [.zip] - may take several seconds...


Overview

Metric Multilign(20) Mastr(seed)
MCC 0.540 > 0.000
Average MCC ± 95% Confidence Intervals 0.536 ± 0.172 > 0.000 ± 0.000
Sensitivity 0.456 > 0.000
Positive Predictive Value 0.647 > 0.000
Total TP 123 > 0
Total TN 34833 < 35023
Total FP 74 > 0
Total FP CONTRA 7 > 0
Total FP INCONS 60 > 0
Total FP COMP 7 > 0
Total FN 147 < 270
P-value 0.0

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Performance plots


  1. Comparison of performance of Multilign(20) and Mastr(seed). Positive Predictive Value (PPV) is plotted against sensitivity. Each dot represents a single test of each method. See tables below for raw data (individual counts for Multilign(20) and Mastr(seed)).

  2. Comparison of average Matthews Correlation Coefficients (MCCs) for Multilign(20) and Mastr(seed). The whiskers correspond to 95% confidence intervals (CIs). 'n' denotes the number of MCCs used to calculate average MCCs and CIs. See tables below for raw data (individual counts for Multilign(20) and Mastr(seed)).

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Performance of Multilign(20) - scored higher in this pairwise comparison

1. Total counts & total scores for Multilign(20)

Total Base Pair Counts
Total TP 123
Total TN 34833
Total FP 74
Total FP CONTRA 7
Total FP INCONS 60
Total FP COMP 7
Total FN 147
Total Scores
MCC 0.540
Average MCC ± 95% Confidence Intervals 0.536 ± 0.172
Sensitivity 0.456
Positive Predictive Value 0.647
Nr of predictions 8

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2. Individual counts for Multilign(20) [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
3AMU_B 0.63 0.56 0.71 15 2982 8 0 6 2 12
3RKF_A 0.77 0.62 0.95 21 2189 1 0 1 0 13
3SD1_A 0.57 0.48 0.69 20 3887 9 1 8 0 22
4A1C_2 0.15 0.15 0.15 5 11747 33 3 26 4 28
4A1C_3 0.70 0.59 0.84 32 7102 6 0 6 0 22
4AOB_A 0.49 0.38 0.64 16 4346 10 1 8 1 26
4ENB_A 0.34 0.26 0.45 5 1264 6 1 5 0 14
4ENC_A 0.65 0.47 0.90 9 1316 1 1 0 0 10

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Performance of Mastr(seed) - scored lower in this pairwise comparison

1. Total counts & total scores for Mastr(seed)

Total Base Pair Counts
Total TP 0
Total TN 35023
Total FP 0
Total FP CONTRA 0
Total FP INCONS 0
Total FP COMP 0
Total FN 270
Total Scores
MCC 0.000
Average MCC ± 95% Confidence Intervals 0.000 ± 0.000
Sensitivity 0.000
Positive Predictive Value 0.000
Nr of predictions 8

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2. Individual counts for Mastr(seed) [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
3AMU_B 0.00 0.00 0.00 0 3003 0 0 0 0 27
3RKF_A 0.00 0.00 0.00 0 2211 0 0 0 0 34
3SD1_A 0.00 0.00 0.00 0 3916 0 0 0 0 42
4A1C_2 0.00 0.00 0.00 0 11781 0 0 0 0 33
4A1C_3 0.00 0.00 0.00 0 7140 0 0 0 0 54
4AOB_A 0.00 0.00 0.00 0 4371 0 0 0 0 42
4ENB_A 0.00 0.00 0.00 0 1275 0 0 0 0 19
4ENC_A 0.00 0.00 0.00 0 1326 0 0 0 0 19

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Matthews Correlation Coeffient, Sensitivity and Positive Predictive Value have been calculated based on the paper by Gardener & Giegerich, 2004.