CompaRNA - on-line benchmarks of RNA structure prediction methods
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Table of contents:

  1. Overview

  2. Performance Plots

  3. Performance of Multilign(20) - scored higher in this pairwise comparison

  4. Performance of RNASLOpt - scored lower in this pairwise comparison

  5. Compile and download dataset for Multilign(20) & RNASLOpt [.zip] - may take several seconds...


Overview

Metric Multilign(20) RNASLOpt
MCC 0.474 > 0.467
Average MCC ± 95% Confidence Intervals 0.466 ± 0.284 < 0.514 ± 0.309
Sensitivity 0.401 > 0.383
Positive Predictive Value 0.568 < 0.577
Total TP 67 > 64
Total TN 25775 < 25782
Total FP 56 > 53
Total FP CONTRA 6 < 11
Total FP INCONS 45 > 36
Total FP COMP 5 < 6
Total FN 100 < 103
P-value 0.0

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Performance plots


  1. Comparison of performance of Multilign(20) and RNASLOpt. Positive Predictive Value (PPV) is plotted against sensitivity. Each dot represents a single test of each method. See tables below for raw data (individual counts for Multilign(20) and RNASLOpt).

  2. Comparison of average Matthews Correlation Coefficients (MCCs) for Multilign(20) and RNASLOpt. The whiskers correspond to 95% confidence intervals (CIs). 'n' denotes the number of MCCs used to calculate average MCCs and CIs. See tables below for raw data (individual counts for Multilign(20) and RNASLOpt).

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Performance of Multilign(20) - scored higher in this pairwise comparison

1. Total counts & total scores for Multilign(20)

Total Base Pair Counts
Total TP 67
Total TN 25775
Total FP 56
Total FP CONTRA 6
Total FP INCONS 45
Total FP COMP 5
Total FN 100
Total Scores
MCC 0.474
Average MCC ± 95% Confidence Intervals 0.466 ± 0.284
Sensitivity 0.401
Positive Predictive Value 0.568
Nr of predictions 5

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2. Individual counts for Multilign(20) [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
4A1C_3 0.70 0.59 0.84 32 7102 6 0 6 0 22
4A1C_2 0.15 0.15 0.15 5 11747 33 3 26 4 28
4AOB_A 0.49 0.38 0.64 16 4346 10 1 8 1 26
4ENB_A 0.34 0.26 0.45 5 1264 6 1 5 0 14
4ENC_A 0.65 0.47 0.90 9 1316 1 1 0 0 10

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Performance of RNASLOpt - scored lower in this pairwise comparison

1. Total counts & total scores for RNASLOpt

Total Base Pair Counts
Total TP 64
Total TN 25782
Total FP 53
Total FP CONTRA 11
Total FP INCONS 36
Total FP COMP 6
Total FN 103
Total Scores
MCC 0.467
Average MCC ± 95% Confidence Intervals 0.514 ± 0.309
Sensitivity 0.383
Positive Predictive Value 0.577
Nr of predictions 5

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2. Individual counts for RNASLOpt [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
4A1C_3 0.67 0.52 0.88 28 7108 4 0 4 0 26
4A1C_2 0.23 0.24 0.22 8 11744 35 8 21 6 25
4AOB_A 0.26 0.19 0.38 8 4350 13 2 11 0 34
4ENB_A 0.76 0.58 1.00 11 1264 0 0 0 0 8
4ENC_A 0.65 0.47 0.90 9 1316 1 1 0 0 10

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Matthews Correlation Coeffient, Sensitivity and Positive Predictive Value have been calculated based on the paper by Gardener & Giegerich, 2004.