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Table of contents:

  1. Overview

  2. Performance Plots

  3. Performance of Multilign(seed) - scored higher in this pairwise comparison

  4. Performance of Mastr(20) - scored lower in this pairwise comparison

  5. Compile and download dataset for Multilign(seed) & Mastr(20) [.zip] - may take several seconds...


Overview

Metric Multilign(seed) Mastr(20)
MCC 0.631 > 0.560
Average MCC ± 95% Confidence Intervals 0.641 ± 0.275 > 0.566 ± 0.406
Sensitivity 0.492 > 0.415
Positive Predictive Value 0.817 > 0.766
Total TP 58 > 49
Total TN 10427 < 10434
Total FP 14 < 16
Total FP CONTRA 1 = 1
Total FP INCONS 12 < 14
Total FP COMP 1 = 1
Total FN 60 < 69
P-value 0.0

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Performance plots


  1. Comparison of performance of Multilign(seed) and Mastr(20). Positive Predictive Value (PPV) is plotted against sensitivity. Each dot represents a single test of each method. See tables below for raw data (individual counts for Multilign(seed) and Mastr(20)).

  2. Comparison of average Matthews Correlation Coefficients (MCCs) for Multilign(seed) and Mastr(20). The whiskers correspond to 95% confidence intervals (CIs). 'n' denotes the number of MCCs used to calculate average MCCs and CIs. See tables below for raw data (individual counts for Multilign(seed) and Mastr(20)).

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Performance of Multilign(seed) - scored higher in this pairwise comparison

1. Total counts & total scores for Multilign(seed)

Total Base Pair Counts
Total TP 58
Total TN 10427
Total FP 14
Total FP CONTRA 1
Total FP INCONS 12
Total FP COMP 1
Total FN 60
Total Scores
MCC 0.631
Average MCC ± 95% Confidence Intervals 0.641 ± 0.275
Sensitivity 0.492
Positive Predictive Value 0.817
Nr of predictions 3

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2. Individual counts for Multilign(seed) [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
3RKF_A 0.76 0.59 1.00 20 2191 0 0 0 0 14
3SD1_A 0.55 0.45 0.68 19 3888 9 1 8 0 23
4AOB_A 0.61 0.45 0.83 19 4348 5 0 4 1 23

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Performance of Mastr(20) - scored lower in this pairwise comparison

1. Total counts & total scores for Mastr(20)

Total Base Pair Counts
Total TP 49
Total TN 10434
Total FP 16
Total FP CONTRA 1
Total FP INCONS 14
Total FP COMP 1
Total FN 69
Total Scores
MCC 0.560
Average MCC ± 95% Confidence Intervals 0.566 ± 0.406
Sensitivity 0.415
Positive Predictive Value 0.766
Nr of predictions 3

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2. Individual counts for Mastr(20) [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
3RKF_A 0.70 0.50 1.00 17 2194 0 0 0 0 17
3SD1_A 0.61 0.50 0.75 21 3888 7 1 6 0 21
4AOB_A 0.39 0.26 0.58 11 4352 9 0 8 1 31

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Matthews Correlation Coeffient, Sensitivity and Positive Predictive Value have been calculated based on the paper by Gardener & Giegerich, 2004.