CompaRNA - on-line benchmarks of RNA structure prediction methods
Home

Methods
Datasets
Rankings
RNA 2D Atlas

Help
FAQ

Contact us
RSS feeds
Twitter

Table of contents:

  1. Overview

  2. Performance Plots

  3. Performance of Multilign(seed) - scored higher in this pairwise comparison

  4. Performance of RDfolder - scored lower in this pairwise comparison

  5. Compile and download dataset for Multilign(seed) & RDfolder [.zip] - may take several seconds...


Overview

Metric Multilign(seed) RDfolder
MCC 0.538 > 0.382
Average MCC ± 95% Confidence Intervals 0.478 ± 0.538 > 0.350 ± 0.507
Sensitivity 0.420 > 0.275
Positive Predictive Value 0.699 > 0.543
Total TP 58 > 38
Total TN 11955 < 11968
Total FP 26 < 33
Total FP CONTRA 2 < 3
Total FP INCONS 23 < 29
Total FP COMP 1 = 1
Total FN 80 < 100
P-value 0.0

^top




Performance plots


  1. Comparison of performance of Multilign(seed) and RDfolder. Positive Predictive Value (PPV) is plotted against sensitivity. Each dot represents a single test of each method. See tables below for raw data (individual counts for Multilign(seed) and RDfolder).

  2. Comparison of average Matthews Correlation Coefficients (MCCs) for Multilign(seed) and RDfolder. The whiskers correspond to 95% confidence intervals (CIs). 'n' denotes the number of MCCs used to calculate average MCCs and CIs. See tables below for raw data (individual counts for Multilign(seed) and RDfolder).

^top





Performance of Multilign(seed) - scored higher in this pairwise comparison

1. Total counts & total scores for Multilign(seed)

Total Base Pair Counts
Total TP 58
Total TN 11955
Total FP 26
Total FP CONTRA 2
Total FP INCONS 23
Total FP COMP 1
Total FN 80
Total Scores
MCC 0.538
Average MCC ± 95% Confidence Intervals 0.478 ± 0.538
Sensitivity 0.420
Positive Predictive Value 0.699
Nr of predictions 4

^top



2. Individual counts for Multilign(seed) [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
2LC8_A -0.01 0.00 0.00 0 1528 12 1 11 0 20
3RKF_A 0.76 0.59 1.00 20 2191 0 0 0 0 14
3SD1_A 0.55 0.45 0.68 19 3888 9 1 8 0 23
4AOB_A 0.61 0.45 0.83 19 4348 5 0 4 1 23

^top



Performance of RDfolder - scored lower in this pairwise comparison

1. Total counts & total scores for RDfolder

Total Base Pair Counts
Total TP 38
Total TN 11968
Total FP 33
Total FP CONTRA 3
Total FP INCONS 29
Total FP COMP 1
Total FN 100
Total Scores
MCC 0.382
Average MCC ± 95% Confidence Intervals 0.350 ± 0.507
Sensitivity 0.275
Positive Predictive Value 0.543
Nr of predictions 4

^top



2. Individual counts for RDfolder [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
2LC8_A -0.01 0.00 0.00 0 1526 14 2 12 0 20
3RKF_A 0.76 0.59 1.00 20 2191 0 0 0 0 14
3SD1_A 0.30 0.17 0.54 7 3903 6 0 6 0 35
4AOB_A 0.35 0.26 0.48 11 4348 13 1 11 1 31

^top


Matthews Correlation Coeffient, Sensitivity and Positive Predictive Value have been calculated based on the paper by Gardener & Giegerich, 2004.