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Table of contents:

  1. Overview

  2. Performance Plots

  3. Performance of Murlet(seed) - scored higher in this pairwise comparison

  4. Performance of Multilign(20) - scored lower in this pairwise comparison

  5. Compile and download dataset for Murlet(seed) & Multilign(20) [.zip] - may take several seconds...


Overview

Metric Murlet(seed) Multilign(20)
MCC 0.520 > 0.480
Average MCC ± 95% Confidence Intervals 0.525 ± 0.052 > 0.493 ± 0.234
Sensitivity 0.296 < 0.402
Positive Predictive Value 0.918 > 0.580
Total TP 56 < 76
Total TN 24819 > 24749
Total FP 6 < 60
Total FP CONTRA 1 < 7
Total FP INCONS 4 < 48
Total FP COMP 1 < 5
Total FN 133 > 113
P-value 0.0

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Performance plots


  1. Comparison of performance of Murlet(seed) and Multilign(20). Positive Predictive Value (PPV) is plotted against sensitivity. Each dot represents a single test of each method. See tables below for raw data (individual counts for Murlet(seed) and Multilign(20)).

  2. Comparison of average Matthews Correlation Coefficients (MCCs) for Murlet(seed) and Multilign(20). The whiskers correspond to 95% confidence intervals (CIs). 'n' denotes the number of MCCs used to calculate average MCCs and CIs. See tables below for raw data (individual counts for Murlet(seed) and Multilign(20)).

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Performance of Murlet(seed) - scored higher in this pairwise comparison

1. Total counts & total scores for Murlet(seed)

Total Base Pair Counts
Total TP 56
Total TN 24819
Total FP 6
Total FP CONTRA 1
Total FP INCONS 4
Total FP COMP 1
Total FN 133
Total Scores
MCC 0.520
Average MCC ± 95% Confidence Intervals 0.525 ± 0.052
Sensitivity 0.296
Positive Predictive Value 0.918
Nr of predictions 6

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2. Individual counts for Murlet(seed) [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
3RKF_A 0.53 0.35 0.80 12 2196 3 1 2 0 22
3SD1_A 0.47 0.26 0.85 11 3903 2 0 2 0 31
4A1C_2 0.46 0.21 1.00 7 11774 0 0 0 0 26
4AOB_A 0.58 0.33 1.00 14 4357 1 0 0 1 28
4ENB_A 0.56 0.32 1.00 6 1269 0 0 0 0 13
4ENC_A 0.56 0.32 1.00 6 1320 0 0 0 0 13

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Performance of Multilign(20) - scored lower in this pairwise comparison

1. Total counts & total scores for Multilign(20)

Total Base Pair Counts
Total TP 76
Total TN 24749
Total FP 60
Total FP CONTRA 7
Total FP INCONS 48
Total FP COMP 5
Total FN 113
Total Scores
MCC 0.480
Average MCC ± 95% Confidence Intervals 0.493 ± 0.234
Sensitivity 0.402
Positive Predictive Value 0.580
Nr of predictions 6

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2. Individual counts for Multilign(20) [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
3RKF_A 0.77 0.62 0.95 21 2189 1 0 1 0 13
3SD1_A 0.57 0.48 0.69 20 3887 9 1 8 0 22
4A1C_2 0.15 0.15 0.15 5 11747 33 3 26 4 28
4AOB_A 0.49 0.38 0.64 16 4346 10 1 8 1 26
4ENB_A 0.34 0.26 0.45 5 1264 6 1 5 0 14
4ENC_A 0.65 0.47 0.90 9 1316 1 1 0 0 10

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Matthews Correlation Coeffient, Sensitivity and Positive Predictive Value have been calculated based on the paper by Gardener & Giegerich, 2004.