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Table of contents:

  1. Overview

  2. Performance Plots

  3. Performance of Murlet(seed) - scored higher in this pairwise comparison

  4. Performance of NanoFolder - scored lower in this pairwise comparison

  5. Compile and download dataset for Murlet(seed) & NanoFolder [.zip] - may take several seconds...


Overview

Metric Murlet(seed) NanoFolder
MCC 0.403 > 0.280
Average MCC ± 95% Confidence Intervals 0.396 ± 0.439 > 0.354 ± 0.414
Sensitivity 0.237 < 0.298
Positive Predictive Value 0.692 > 0.272
Total TP 27 < 34
Total TN 18979 > 18893
Total FP 13 < 101
Total FP CONTRA 0 < 13
Total FP INCONS 12 < 78
Total FP COMP 1 < 10
Total FN 87 > 80
P-value 0.0

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Performance plots


  1. Comparison of performance of Murlet(seed) and NanoFolder. Positive Predictive Value (PPV) is plotted against sensitivity. Each dot represents a single test of each method. See tables below for raw data (individual counts for Murlet(seed) and NanoFolder).

  2. Comparison of average Matthews Correlation Coefficients (MCCs) for Murlet(seed) and NanoFolder. The whiskers correspond to 95% confidence intervals (CIs). 'n' denotes the number of MCCs used to calculate average MCCs and CIs. See tables below for raw data (individual counts for Murlet(seed) and NanoFolder).

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Performance of Murlet(seed) - scored higher in this pairwise comparison

1. Total counts & total scores for Murlet(seed)

Total Base Pair Counts
Total TP 27
Total TN 18979
Total FP 13
Total FP CONTRA 0
Total FP INCONS 12
Total FP COMP 1
Total FN 87
Total Scores
MCC 0.403
Average MCC ± 95% Confidence Intervals 0.396 ± 0.439
Sensitivity 0.237
Positive Predictive Value 0.692
Nr of predictions 4

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2. Individual counts for Murlet(seed) [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
2LC8_A -0.01 0.00 0.00 0 1528 12 0 12 0 20
4A1C_2 0.46 0.21 1.00 7 11774 0 0 0 0 26
4AOB_A 0.58 0.33 1.00 14 4357 1 0 0 1 28
4ENC_A 0.56 0.32 1.00 6 1320 0 0 0 0 13

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Performance of NanoFolder - scored lower in this pairwise comparison

1. Total counts & total scores for NanoFolder

Total Base Pair Counts
Total TP 34
Total TN 18893
Total FP 101
Total FP CONTRA 13
Total FP INCONS 78
Total FP COMP 10
Total FN 80
Total Scores
MCC 0.280
Average MCC ± 95% Confidence Intervals 0.354 ± 0.414
Sensitivity 0.298
Positive Predictive Value 0.272
Nr of predictions 4

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2. Individual counts for NanoFolder [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
2LC8_A 0.52 0.55 0.50 11 1518 11 0 11 0 9
4A1C_2 0.00 0.00 0.00 0 11728 61 12 41 8 33
4AOB_A 0.33 0.29 0.39 12 4340 20 1 18 1 30
4ENC_A 0.57 0.58 0.58 11 1307 9 0 8 1 8

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Matthews Correlation Coeffient, Sensitivity and Positive Predictive Value have been calculated based on the paper by Gardener & Giegerich, 2004.