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Table of contents:

  1. Overview

  2. Performance Plots

  3. Performance of PETfold_pre2.0(20) - scored higher in this pairwise comparison

  4. Performance of Afold - scored lower in this pairwise comparison

  5. Compile and download dataset for PETfold_pre2.0(20) & Afold [.zip] - may take several seconds...


Overview

Metric PETfold_pre2.0(20) Afold
MCC 0.333 > 0.311
Average MCC ± 95% Confidence Intervals 0.401 ± 2.639 < 0.406 ± 3.353
Sensitivity 0.250 < 0.308
Positive Predictive Value 0.448 > 0.320
Total TP 13 < 16
Total TN 13027 > 13006
Total FP 26 < 46
Total FP CONTRA 0 < 6
Total FP INCONS 16 < 28
Total FP COMP 10 < 12
Total FN 39 > 36
P-value 0.0

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Performance plots


  1. Comparison of performance of PETfold_pre2.0(20) and Afold. Positive Predictive Value (PPV) is plotted against sensitivity. Each dot represents a single test of each method. See tables below for raw data (individual counts for PETfold_pre2.0(20) and Afold).

  2. Comparison of average Matthews Correlation Coefficients (MCCs) for PETfold_pre2.0(20) and Afold. The whiskers correspond to 95% confidence intervals (CIs). 'n' denotes the number of MCCs used to calculate average MCCs and CIs. See tables below for raw data (individual counts for PETfold_pre2.0(20) and Afold).

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Performance of PETfold_pre2.0(20) - scored higher in this pairwise comparison

1. Total counts & total scores for PETfold_pre2.0(20)

Total Base Pair Counts
Total TP 13
Total TN 13027
Total FP 26
Total FP CONTRA 0
Total FP INCONS 16
Total FP COMP 10
Total FN 39
Total Scores
MCC 0.333
Average MCC ± 95% Confidence Intervals 0.401 ± 2.639
Sensitivity 0.250
Positive Predictive Value 0.448
Nr of predictions 2

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2. Individual counts for PETfold_pre2.0(20) [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
4A1C_2 0.19 0.15 0.25 5 11761 25 0 15 10 28
4ENB_A 0.61 0.42 0.89 8 1266 1 0 1 0 11

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Performance of Afold - scored lower in this pairwise comparison

1. Total counts & total scores for Afold

Total Base Pair Counts
Total TP 16
Total TN 13006
Total FP 46
Total FP CONTRA 6
Total FP INCONS 28
Total FP COMP 12
Total FN 36
Total Scores
MCC 0.311
Average MCC ± 95% Confidence Intervals 0.406 ± 3.353
Sensitivity 0.308
Positive Predictive Value 0.320
Nr of predictions 2

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2. Individual counts for Afold [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
4A1C_2 0.14 0.15 0.14 5 11745 43 5 26 12 28
4ENB_A 0.67 0.58 0.79 11 1261 3 1 2 0 8

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Matthews Correlation Coeffient, Sensitivity and Positive Predictive Value have been calculated based on the paper by Gardener & Giegerich, 2004.