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Table of contents:

  1. Overview

  2. Performance Plots

  3. Performance of PETfold_pre2.0(20) - scored higher in this pairwise comparison

  4. Performance of Contrafold - scored lower in this pairwise comparison

  5. Compile and download dataset for PETfold_pre2.0(20) & Contrafold [.zip] - may take several seconds...


Overview

Metric PETfold_pre2.0(20) Contrafold
MCC 0.625 > 0.511
Average MCC ± 95% Confidence Intervals 0.581 ± 0.300 > 0.543 ± 0.305
Sensitivity 0.497 > 0.437
Positive Predictive Value 0.790 > 0.603
Total TP 83 > 73
Total TN 25788 > 25772
Total FP 33 < 57
Total FP CONTRA 0 < 9
Total FP INCONS 22 < 39
Total FP COMP 11 > 9
Total FN 84 < 94
P-value 0.0

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Performance plots


  1. Comparison of performance of PETfold_pre2.0(20) and Contrafold. Positive Predictive Value (PPV) is plotted against sensitivity. Each dot represents a single test of each method. See tables below for raw data (individual counts for PETfold_pre2.0(20) and Contrafold).

  2. Comparison of average Matthews Correlation Coefficients (MCCs) for PETfold_pre2.0(20) and Contrafold. The whiskers correspond to 95% confidence intervals (CIs). 'n' denotes the number of MCCs used to calculate average MCCs and CIs. See tables below for raw data (individual counts for PETfold_pre2.0(20) and Contrafold).

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Performance of PETfold_pre2.0(20) - scored higher in this pairwise comparison

1. Total counts & total scores for PETfold_pre2.0(20)

Total Base Pair Counts
Total TP 83
Total TN 25788
Total FP 33
Total FP CONTRA 0
Total FP INCONS 22
Total FP COMP 11
Total FN 84
Total Scores
MCC 0.625
Average MCC ± 95% Confidence Intervals 0.581 ± 0.300
Sensitivity 0.497
Positive Predictive Value 0.790
Nr of predictions 5

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2. Individual counts for PETfold_pre2.0(20) [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
4A1C_3 0.82 0.69 0.97 37 7102 1 0 1 0 17
4A1C_2 0.19 0.15 0.25 5 11761 25 0 15 10 28
4AOB_A 0.74 0.60 0.93 25 4344 3 0 2 1 17
4ENB_A 0.61 0.42 0.89 8 1266 1 0 1 0 11
4ENC_A 0.55 0.42 0.73 8 1315 3 0 3 0 11

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Performance of Contrafold - scored lower in this pairwise comparison

1. Total counts & total scores for Contrafold

Total Base Pair Counts
Total TP 73
Total TN 25772
Total FP 57
Total FP CONTRA 9
Total FP INCONS 39
Total FP COMP 9
Total FN 94
Total Scores
MCC 0.511
Average MCC ± 95% Confidence Intervals 0.543 ± 0.305
Sensitivity 0.437
Positive Predictive Value 0.603
Nr of predictions 5

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2. Individual counts for Contrafold [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
4A1C_3 0.66 0.57 0.78 31 7100 9 1 8 0 23
4A1C_2 0.16 0.15 0.17 5 11751 33 5 20 8 28
4AOB_A 0.44 0.36 0.56 15 4344 13 1 11 1 27
4ENB_A 0.73 0.58 0.92 11 1263 1 1 0 0 8
4ENC_A 0.73 0.58 0.92 11 1314 1 1 0 0 8

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Matthews Correlation Coeffient, Sensitivity and Positive Predictive Value have been calculated based on the paper by Gardener & Giegerich, 2004.