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Table of contents:

  1. Overview

  2. Performance Plots

  3. Performance of PETfold_pre2.0(20) - scored higher in this pairwise comparison

  4. Performance of Cylofold - scored lower in this pairwise comparison

  5. Compile and download dataset for PETfold_pre2.0(20) & Cylofold [.zip] - may take several seconds...


Overview

Metric PETfold_pre2.0(20) Cylofold
MCC 0.666 > 0.620
Average MCC ± 95% Confidence Intervals 0.632 ± 0.244 < 0.698 ± 0.751
Sensitivity 0.513 = 0.513
Positive Predictive Value 0.872 > 0.759
Total TP 41 = 41
Total TN 6925 > 6918
Total FP 7 < 14
Total FP CONTRA 0 < 2
Total FP INCONS 6 < 11
Total FP COMP 1 = 1
Total FN 39 = 39
P-value 0.0

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Performance plots


  1. Comparison of performance of PETfold_pre2.0(20) and Cylofold. Positive Predictive Value (PPV) is plotted against sensitivity. Each dot represents a single test of each method. See tables below for raw data (individual counts for PETfold_pre2.0(20) and Cylofold).

  2. Comparison of average Matthews Correlation Coefficients (MCCs) for PETfold_pre2.0(20) and Cylofold. The whiskers correspond to 95% confidence intervals (CIs). 'n' denotes the number of MCCs used to calculate average MCCs and CIs. See tables below for raw data (individual counts for PETfold_pre2.0(20) and Cylofold).

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Performance of PETfold_pre2.0(20) - scored higher in this pairwise comparison

1. Total counts & total scores for PETfold_pre2.0(20)

Total Base Pair Counts
Total TP 41
Total TN 6925
Total FP 7
Total FP CONTRA 0
Total FP INCONS 6
Total FP COMP 1
Total FN 39
Total Scores
MCC 0.666
Average MCC ± 95% Confidence Intervals 0.632 ± 0.244
Sensitivity 0.513
Positive Predictive Value 0.872
Nr of predictions 3

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2. Individual counts for PETfold_pre2.0(20) [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
4AOB_A 0.74 0.60 0.93 25 4344 3 0 2 1 17
4ENB_A 0.61 0.42 0.89 8 1266 1 0 1 0 11
4ENC_A 0.55 0.42 0.73 8 1315 3 0 3 0 11

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Performance of Cylofold - scored lower in this pairwise comparison

1. Total counts & total scores for Cylofold

Total Base Pair Counts
Total TP 41
Total TN 6918
Total FP 14
Total FP CONTRA 2
Total FP INCONS 11
Total FP COMP 1
Total FN 39
Total Scores
MCC 0.620
Average MCC ± 95% Confidence Intervals 0.698 ± 0.751
Sensitivity 0.513
Positive Predictive Value 0.759
Nr of predictions 3

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2. Individual counts for Cylofold [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
4AOB_A 0.35 0.26 0.48 11 4348 13 1 11 1 31
4ENB_A 0.89 0.79 1.00 15 1260 0 0 0 0 4
4ENC_A 0.86 0.79 0.94 15 1310 1 1 0 0 4

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Matthews Correlation Coeffient, Sensitivity and Positive Predictive Value have been calculated based on the paper by Gardener & Giegerich, 2004.