CompaRNA - on-line benchmarks of RNA structure prediction methods
Home

Methods
Datasets
Rankings
RNA 2D Atlas

Help
FAQ

Contact us
RSS feeds
Twitter

Table of contents:

  1. Overview

  2. Performance Plots

  3. Performance of PETfold_pre2.0(20) - scored higher in this pairwise comparison

  4. Performance of IPknot - scored lower in this pairwise comparison

  5. Compile and download dataset for PETfold_pre2.0(20) & IPknot [.zip] - may take several seconds...


Overview

Metric PETfold_pre2.0(20) IPknot
MCC 0.625 > 0.502
Average MCC ± 95% Confidence Intervals 0.581 ± 0.300 > 0.513 ± 0.291
Sensitivity 0.497 > 0.413
Positive Predictive Value 0.790 > 0.616
Total TP 83 > 69
Total TN 25788 > 25781
Total FP 33 < 49
Total FP CONTRA 0 < 6
Total FP INCONS 22 < 37
Total FP COMP 11 > 6
Total FN 84 < 98
P-value 0.0

^top




Performance plots


  1. Comparison of performance of PETfold_pre2.0(20) and IPknot. Positive Predictive Value (PPV) is plotted against sensitivity. Each dot represents a single test of each method. See tables below for raw data (individual counts for PETfold_pre2.0(20) and IPknot).

  2. Comparison of average Matthews Correlation Coefficients (MCCs) for PETfold_pre2.0(20) and IPknot. The whiskers correspond to 95% confidence intervals (CIs). 'n' denotes the number of MCCs used to calculate average MCCs and CIs. See tables below for raw data (individual counts for PETfold_pre2.0(20) and IPknot).

^top





Performance of PETfold_pre2.0(20) - scored higher in this pairwise comparison

1. Total counts & total scores for PETfold_pre2.0(20)

Total Base Pair Counts
Total TP 83
Total TN 25788
Total FP 33
Total FP CONTRA 0
Total FP INCONS 22
Total FP COMP 11
Total FN 84
Total Scores
MCC 0.625
Average MCC ± 95% Confidence Intervals 0.581 ± 0.300
Sensitivity 0.497
Positive Predictive Value 0.790
Nr of predictions 5

^top



2. Individual counts for PETfold_pre2.0(20) [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
4A1C_3 0.82 0.69 0.97 37 7102 1 0 1 0 17
4A1C_2 0.19 0.15 0.25 5 11761 25 0 15 10 28
4AOB_A 0.74 0.60 0.93 25 4344 3 0 2 1 17
4ENB_A 0.61 0.42 0.89 8 1266 1 0 1 0 11
4ENC_A 0.55 0.42 0.73 8 1315 3 0 3 0 11

^top



Performance of IPknot - scored lower in this pairwise comparison

1. Total counts & total scores for IPknot

Total Base Pair Counts
Total TP 69
Total TN 25781
Total FP 49
Total FP CONTRA 6
Total FP INCONS 37
Total FP COMP 6
Total FN 98
Total Scores
MCC 0.502
Average MCC ± 95% Confidence Intervals 0.513 ± 0.291
Sensitivity 0.413
Positive Predictive Value 0.616
Nr of predictions 5

^top



2. Individual counts for IPknot [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
4A1C_3 0.69 0.57 0.84 31 7103 6 1 5 0 23
4A1C_2 0.17 0.15 0.19 5 11755 26 4 17 5 28
4AOB_A 0.42 0.33 0.54 14 4345 13 1 11 1 28
4ENB_A 0.76 0.58 1.00 11 1264 0 0 0 0 8
4ENC_A 0.52 0.42 0.67 8 1314 4 0 4 0 11

^top


Matthews Correlation Coeffient, Sensitivity and Positive Predictive Value have been calculated based on the paper by Gardener & Giegerich, 2004.