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Table of contents:

  1. Overview

  2. Performance Plots

  3. Performance of PETfold_pre2.0(20) - scored higher in this pairwise comparison

  4. Performance of Mastr(20) - scored lower in this pairwise comparison

  5. Compile and download dataset for PETfold_pre2.0(20) & Mastr(20) [.zip] - may take several seconds...


Overview

Metric PETfold_pre2.0(20) Mastr(20)
MCC 0.625 > 0.488
Average MCC ± 95% Confidence Intervals 0.581 ± 0.300 > 0.399 ± 0.320
Sensitivity 0.497 > 0.305
Positive Predictive Value 0.790 > 0.785
Total TP 83 > 51
Total TN 25788 < 25828
Total FP 33 > 16
Total FP CONTRA 0 = 0
Total FP INCONS 22 > 14
Total FP COMP 11 > 2
Total FN 84 < 116
P-value 0.0

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Performance plots


  1. Comparison of performance of PETfold_pre2.0(20) and Mastr(20). Positive Predictive Value (PPV) is plotted against sensitivity. Each dot represents a single test of each method. See tables below for raw data (individual counts for PETfold_pre2.0(20) and Mastr(20)).

  2. Comparison of average Matthews Correlation Coefficients (MCCs) for PETfold_pre2.0(20) and Mastr(20). The whiskers correspond to 95% confidence intervals (CIs). 'n' denotes the number of MCCs used to calculate average MCCs and CIs. See tables below for raw data (individual counts for PETfold_pre2.0(20) and Mastr(20)).

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Performance of PETfold_pre2.0(20) - scored higher in this pairwise comparison

1. Total counts & total scores for PETfold_pre2.0(20)

Total Base Pair Counts
Total TP 83
Total TN 25788
Total FP 33
Total FP CONTRA 0
Total FP INCONS 22
Total FP COMP 11
Total FN 84
Total Scores
MCC 0.625
Average MCC ± 95% Confidence Intervals 0.581 ± 0.300
Sensitivity 0.497
Positive Predictive Value 0.790
Nr of predictions 5

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2. Individual counts for PETfold_pre2.0(20) [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
4A1C_3 0.82 0.69 0.97 37 7102 1 0 1 0 17
4A1C_2 0.19 0.15 0.25 5 11761 25 0 15 10 28
4AOB_A 0.74 0.60 0.93 25 4344 3 0 2 1 17
4ENB_A 0.61 0.42 0.89 8 1266 1 0 1 0 11
4ENC_A 0.55 0.42 0.73 8 1315 3 0 3 0 11

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Performance of Mastr(20) - scored lower in this pairwise comparison

1. Total counts & total scores for Mastr(20)

Total Base Pair Counts
Total TP 51
Total TN 25828
Total FP 16
Total FP CONTRA 0
Total FP INCONS 14
Total FP COMP 2
Total FN 116
Total Scores
MCC 0.488
Average MCC ± 95% Confidence Intervals 0.399 ± 0.320
Sensitivity 0.305
Positive Predictive Value 0.785
Nr of predictions 5

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2. Individual counts for Mastr(20) [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
4A1C_3 0.70 0.59 0.84 32 7102 7 0 6 1 22
4A1C_2 0.00 0.00 0.00 0 11781 0 0 0 0 33
4AOB_A 0.39 0.26 0.58 11 4352 9 0 8 1 31
4ENB_A 0.39 0.16 1.00 3 1272 0 0 0 0 16
4ENC_A 0.51 0.26 1.00 5 1321 0 0 0 0 14

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Matthews Correlation Coeffient, Sensitivity and Positive Predictive Value have been calculated based on the paper by Gardener & Giegerich, 2004.