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Table of contents:

  1. Overview

  2. Performance Plots

  3. Performance of PETfold_pre2.0(20) - scored higher in this pairwise comparison

  4. Performance of PPfold(20) - scored lower in this pairwise comparison

  5. Compile and download dataset for PETfold_pre2.0(20) & PPfold(20) [.zip] - may take several seconds...


Overview

Metric PETfold_pre2.0(20) PPfold(20)
MCC 0.625 > 0.616
Average MCC ± 95% Confidence Intervals 0.581 ± 0.300 > 0.572 ± 0.277
Sensitivity 0.497 > 0.473
Positive Predictive Value 0.790 < 0.806
Total TP 83 > 79
Total TN 25788 < 25795
Total FP 33 > 24
Total FP CONTRA 0 = 0
Total FP INCONS 22 > 19
Total FP COMP 11 > 5
Total FN 84 < 88
P-value 0.0

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Performance plots


  1. Comparison of performance of PETfold_pre2.0(20) and PPfold(20). Positive Predictive Value (PPV) is plotted against sensitivity. Each dot represents a single test of each method. See tables below for raw data (individual counts for PETfold_pre2.0(20) and PPfold(20)).

  2. Comparison of average Matthews Correlation Coefficients (MCCs) for PETfold_pre2.0(20) and PPfold(20). The whiskers correspond to 95% confidence intervals (CIs). 'n' denotes the number of MCCs used to calculate average MCCs and CIs. See tables below for raw data (individual counts for PETfold_pre2.0(20) and PPfold(20)).

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Performance of PETfold_pre2.0(20) - scored higher in this pairwise comparison

1. Total counts & total scores for PETfold_pre2.0(20)

Total Base Pair Counts
Total TP 83
Total TN 25788
Total FP 33
Total FP CONTRA 0
Total FP INCONS 22
Total FP COMP 11
Total FN 84
Total Scores
MCC 0.625
Average MCC ± 95% Confidence Intervals 0.581 ± 0.300
Sensitivity 0.497
Positive Predictive Value 0.790
Nr of predictions 5

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2. Individual counts for PETfold_pre2.0(20) [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
4A1C_3 0.82 0.69 0.97 37 7102 1 0 1 0 17
4A1C_2 0.19 0.15 0.25 5 11761 25 0 15 10 28
4AOB_A 0.74 0.60 0.93 25 4344 3 0 2 1 17
4ENB_A 0.61 0.42 0.89 8 1266 1 0 1 0 11
4ENC_A 0.55 0.42 0.73 8 1315 3 0 3 0 11

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Performance of PPfold(20) - scored lower in this pairwise comparison

1. Total counts & total scores for PPfold(20)

Total Base Pair Counts
Total TP 79
Total TN 25795
Total FP 24
Total FP CONTRA 0
Total FP INCONS 19
Total FP COMP 5
Total FN 88
Total Scores
MCC 0.616
Average MCC ± 95% Confidence Intervals 0.572 ± 0.277
Sensitivity 0.473
Positive Predictive Value 0.806
Nr of predictions 5

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2. Individual counts for PPfold(20) [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
4A1C_3 0.77 0.63 0.94 34 7104 2 0 2 0 20
4A1C_2 0.21 0.15 0.29 5 11764 16 0 12 4 28
4AOB_A 0.74 0.60 0.93 25 4344 3 0 2 1 17
4ENB_A 0.56 0.37 0.88 7 1267 1 0 1 0 12
4ENC_A 0.58 0.42 0.80 8 1316 2 0 2 0 11

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Matthews Correlation Coeffient, Sensitivity and Positive Predictive Value have been calculated based on the paper by Gardener & Giegerich, 2004.