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Table of contents:

  1. Overview

  2. Performance Plots

  3. Performance of PETfold_pre2.0(20) - scored higher in this pairwise comparison

  4. Performance of PknotsRG - scored lower in this pairwise comparison

  5. Compile and download dataset for PETfold_pre2.0(20) & PknotsRG [.zip] - may take several seconds...


Overview

Metric PETfold_pre2.0(20) PknotsRG
MCC 0.625 > 0.555
Average MCC ± 95% Confidence Intervals 0.581 ± 0.300 < 0.616 ± 0.383
Sensitivity 0.497 < 0.503
Positive Predictive Value 0.790 > 0.618
Total TP 83 < 84
Total TN 25788 > 25757
Total FP 33 < 62
Total FP CONTRA 0 < 9
Total FP INCONS 22 < 43
Total FP COMP 11 > 10
Total FN 84 > 83
P-value 0.0

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Performance plots


  1. Comparison of performance of PETfold_pre2.0(20) and PknotsRG. Positive Predictive Value (PPV) is plotted against sensitivity. Each dot represents a single test of each method. See tables below for raw data (individual counts for PETfold_pre2.0(20) and PknotsRG).

  2. Comparison of average Matthews Correlation Coefficients (MCCs) for PETfold_pre2.0(20) and PknotsRG. The whiskers correspond to 95% confidence intervals (CIs). 'n' denotes the number of MCCs used to calculate average MCCs and CIs. See tables below for raw data (individual counts for PETfold_pre2.0(20) and PknotsRG).

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Performance of PETfold_pre2.0(20) - scored higher in this pairwise comparison

1. Total counts & total scores for PETfold_pre2.0(20)

Total Base Pair Counts
Total TP 83
Total TN 25788
Total FP 33
Total FP CONTRA 0
Total FP INCONS 22
Total FP COMP 11
Total FN 84
Total Scores
MCC 0.625
Average MCC ± 95% Confidence Intervals 0.581 ± 0.300
Sensitivity 0.497
Positive Predictive Value 0.790
Nr of predictions 5

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2. Individual counts for PETfold_pre2.0(20) [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
4A1C_3 0.82 0.69 0.97 37 7102 1 0 1 0 17
4A1C_2 0.19 0.15 0.25 5 11761 25 0 15 10 28
4AOB_A 0.74 0.60 0.93 25 4344 3 0 2 1 17
4ENB_A 0.61 0.42 0.89 8 1266 1 0 1 0 11
4ENC_A 0.55 0.42 0.73 8 1315 3 0 3 0 11

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Performance of PknotsRG - scored lower in this pairwise comparison

1. Total counts & total scores for PknotsRG

Total Base Pair Counts
Total TP 84
Total TN 25757
Total FP 62
Total FP CONTRA 9
Total FP INCONS 43
Total FP COMP 10
Total FN 83
Total Scores
MCC 0.555
Average MCC ± 95% Confidence Intervals 0.616 ± 0.383
Sensitivity 0.503
Positive Predictive Value 0.618
Nr of predictions 5

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2. Individual counts for PknotsRG [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
4A1C_3 0.70 0.59 0.82 32 7101 7 1 6 0 22
4A1C_2 0.14 0.15 0.13 5 11742 43 5 29 9 28
4AOB_A 0.50 0.40 0.63 17 4344 11 2 8 1 25
4ENB_A 0.89 0.79 1.00 15 1260 0 0 0 0 4
4ENC_A 0.86 0.79 0.94 15 1310 1 1 0 0 4

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Matthews Correlation Coeffient, Sensitivity and Positive Predictive Value have been calculated based on the paper by Gardener & Giegerich, 2004.