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Table of contents:

  1. Overview

  2. Performance Plots

  3. Performance of PETfold_pre2.0(20) - scored higher in this pairwise comparison

  4. Performance of RNAwolf - scored lower in this pairwise comparison

  5. Compile and download dataset for PETfold_pre2.0(20) & RNAwolf [.zip] - may take several seconds...


Overview

Metric PETfold_pre2.0(20) RNAwolf
MCC 0.625 > 0.220
Average MCC ± 95% Confidence Intervals 0.581 ± 0.300 > 0.246 ± 0.133
Sensitivity 0.497 > 0.204
Positive Predictive Value 0.790 > 0.248
Total TP 83 > 34
Total TN 25788 > 25756
Total FP 33 < 113
Total FP CONTRA 0 < 15
Total FP INCONS 22 < 88
Total FP COMP 11 > 10
Total FN 84 < 133
P-value 0.0

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Performance plots


  1. Comparison of performance of PETfold_pre2.0(20) and RNAwolf. Positive Predictive Value (PPV) is plotted against sensitivity. Each dot represents a single test of each method. See tables below for raw data (individual counts for PETfold_pre2.0(20) and RNAwolf).

  2. Comparison of average Matthews Correlation Coefficients (MCCs) for PETfold_pre2.0(20) and RNAwolf. The whiskers correspond to 95% confidence intervals (CIs). 'n' denotes the number of MCCs used to calculate average MCCs and CIs. See tables below for raw data (individual counts for PETfold_pre2.0(20) and RNAwolf).

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Performance of PETfold_pre2.0(20) - scored higher in this pairwise comparison

1. Total counts & total scores for PETfold_pre2.0(20)

Total Base Pair Counts
Total TP 83
Total TN 25788
Total FP 33
Total FP CONTRA 0
Total FP INCONS 22
Total FP COMP 11
Total FN 84
Total Scores
MCC 0.625
Average MCC ± 95% Confidence Intervals 0.581 ± 0.300
Sensitivity 0.497
Positive Predictive Value 0.790
Nr of predictions 5

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2. Individual counts for PETfold_pre2.0(20) [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
4A1C_3 0.82 0.69 0.97 37 7102 1 0 1 0 17
4A1C_2 0.19 0.15 0.25 5 11761 25 0 15 10 28
4AOB_A 0.74 0.60 0.93 25 4344 3 0 2 1 17
4ENB_A 0.61 0.42 0.89 8 1266 1 0 1 0 11
4ENC_A 0.55 0.42 0.73 8 1315 3 0 3 0 11

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Performance of RNAwolf - scored lower in this pairwise comparison

1. Total counts & total scores for RNAwolf

Total Base Pair Counts
Total TP 34
Total TN 25756
Total FP 113
Total FP CONTRA 15
Total FP INCONS 88
Total FP COMP 10
Total FN 133
Total Scores
MCC 0.220
Average MCC ± 95% Confidence Intervals 0.246 ± 0.133
Sensitivity 0.204
Positive Predictive Value 0.248
Nr of predictions 5

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2. Individual counts for RNAwolf [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
4A1C_3 0.23 0.20 0.28 11 7101 28 2 26 0 43
4A1C_2 0.08 0.09 0.08 3 11741 46 10 27 9 30
4AOB_A 0.23 0.19 0.30 8 4344 20 1 18 1 34
4ENB_A 0.35 0.32 0.40 6 1260 9 1 8 0 13
4ENC_A 0.34 0.32 0.38 6 1310 10 1 9 0 13

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Matthews Correlation Coeffient, Sensitivity and Positive Predictive Value have been calculated based on the paper by Gardener & Giegerich, 2004.