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Table of contents:

  1. Overview

  2. Performance Plots

  3. Performance of PETfold_pre2.0(20) - scored higher in this pairwise comparison

  4. Performance of RSpredict(20) - scored lower in this pairwise comparison

  5. Compile and download dataset for PETfold_pre2.0(20) & RSpredict(20) [.zip] - may take several seconds...


Overview

Metric PETfold_pre2.0(20) RSpredict(20)
MCC 0.625 > 0.352
Average MCC ± 95% Confidence Intervals 0.581 ± 0.300 > 0.376 ± 0.168
Sensitivity 0.497 > 0.251
Positive Predictive Value 0.790 > 0.500
Total TP 83 > 42
Total TN 25788 < 25809
Total FP 33 < 48
Total FP CONTRA 0 < 6
Total FP INCONS 22 < 36
Total FP COMP 11 > 6
Total FN 84 < 125
P-value 0.0

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Performance plots


  1. Comparison of performance of PETfold_pre2.0(20) and RSpredict(20). Positive Predictive Value (PPV) is plotted against sensitivity. Each dot represents a single test of each method. See tables below for raw data (individual counts for PETfold_pre2.0(20) and RSpredict(20)).

  2. Comparison of average Matthews Correlation Coefficients (MCCs) for PETfold_pre2.0(20) and RSpredict(20). The whiskers correspond to 95% confidence intervals (CIs). 'n' denotes the number of MCCs used to calculate average MCCs and CIs. See tables below for raw data (individual counts for PETfold_pre2.0(20) and RSpredict(20)).

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Performance of PETfold_pre2.0(20) - scored higher in this pairwise comparison

1. Total counts & total scores for PETfold_pre2.0(20)

Total Base Pair Counts
Total TP 83
Total TN 25788
Total FP 33
Total FP CONTRA 0
Total FP INCONS 22
Total FP COMP 11
Total FN 84
Total Scores
MCC 0.625
Average MCC ± 95% Confidence Intervals 0.581 ± 0.300
Sensitivity 0.497
Positive Predictive Value 0.790
Nr of predictions 5

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2. Individual counts for PETfold_pre2.0(20) [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
4A1C_3 0.82 0.69 0.97 37 7102 1 0 1 0 17
4A1C_2 0.19 0.15 0.25 5 11761 25 0 15 10 28
4AOB_A 0.74 0.60 0.93 25 4344 3 0 2 1 17
4ENB_A 0.61 0.42 0.89 8 1266 1 0 1 0 11
4ENC_A 0.55 0.42 0.73 8 1315 3 0 3 0 11

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Performance of RSpredict(20) - scored lower in this pairwise comparison

1. Total counts & total scores for RSpredict(20)

Total Base Pair Counts
Total TP 42
Total TN 25809
Total FP 48
Total FP CONTRA 6
Total FP INCONS 36
Total FP COMP 6
Total FN 125
Total Scores
MCC 0.352
Average MCC ± 95% Confidence Intervals 0.376 ± 0.168
Sensitivity 0.251
Positive Predictive Value 0.500
Nr of predictions 5

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2. Individual counts for RSpredict(20) [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
4A1C_3 0.48 0.33 0.69 18 7114 8 0 8 0 36
4A1C_2 0.19 0.18 0.20 6 11751 30 6 18 6 27
4AOB_A 0.28 0.14 0.55 6 4360 5 0 5 0 36
4ENB_A 0.48 0.32 0.75 6 1267 2 0 2 0 13
4ENC_A 0.45 0.32 0.67 6 1317 3 0 3 0 13

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Matthews Correlation Coeffient, Sensitivity and Positive Predictive Value have been calculated based on the paper by Gardener & Giegerich, 2004.