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Table of contents:

  1. Overview

  2. Performance Plots

  3. Performance of PETfold_pre2.0(20) - scored higher in this pairwise comparison

  4. Performance of RSpredict(seed) - scored lower in this pairwise comparison

  5. Compile and download dataset for PETfold_pre2.0(20) & RSpredict(seed) [.zip] - may take several seconds...


Overview

Metric PETfold_pre2.0(20) RSpredict(seed)
MCC 0.625 > 0.184
Average MCC ± 95% Confidence Intervals 0.581 ± 0.300 > 0.190 ± 0.219
Sensitivity 0.497 > 0.072
Positive Predictive Value 0.790 > 0.480
Total TP 83 > 12
Total TN 25788 < 25868
Total FP 33 > 14
Total FP CONTRA 0 < 2
Total FP INCONS 22 > 11
Total FP COMP 11 > 1
Total FN 84 < 155
P-value 0.0

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Performance plots


  1. Comparison of performance of PETfold_pre2.0(20) and RSpredict(seed). Positive Predictive Value (PPV) is plotted against sensitivity. Each dot represents a single test of each method. See tables below for raw data (individual counts for PETfold_pre2.0(20) and RSpredict(seed)).

  2. Comparison of average Matthews Correlation Coefficients (MCCs) for PETfold_pre2.0(20) and RSpredict(seed). The whiskers correspond to 95% confidence intervals (CIs). 'n' denotes the number of MCCs used to calculate average MCCs and CIs. See tables below for raw data (individual counts for PETfold_pre2.0(20) and RSpredict(seed)).

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Performance of PETfold_pre2.0(20) - scored higher in this pairwise comparison

1. Total counts & total scores for PETfold_pre2.0(20)

Total Base Pair Counts
Total TP 83
Total TN 25788
Total FP 33
Total FP CONTRA 0
Total FP INCONS 22
Total FP COMP 11
Total FN 84
Total Scores
MCC 0.625
Average MCC ± 95% Confidence Intervals 0.581 ± 0.300
Sensitivity 0.497
Positive Predictive Value 0.790
Nr of predictions 5

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2. Individual counts for PETfold_pre2.0(20) [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
4A1C_3 0.82 0.69 0.97 37 7102 1 0 1 0 17
4A1C_2 0.19 0.15 0.25 5 11761 25 0 15 10 28
4AOB_A 0.74 0.60 0.93 25 4344 3 0 2 1 17
4ENB_A 0.61 0.42 0.89 8 1266 1 0 1 0 11
4ENC_A 0.55 0.42 0.73 8 1315 3 0 3 0 11

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Performance of RSpredict(seed) - scored lower in this pairwise comparison

1. Total counts & total scores for RSpredict(seed)

Total Base Pair Counts
Total TP 12
Total TN 25868
Total FP 14
Total FP CONTRA 2
Total FP INCONS 11
Total FP COMP 1
Total FN 155
Total Scores
MCC 0.184
Average MCC ± 95% Confidence Intervals 0.190 ± 0.219
Sensitivity 0.072
Positive Predictive Value 0.480
Nr of predictions 5

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2. Individual counts for RSpredict(seed) [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
4A1C_3 0.00 0.00 0.00 0 7136 4 1 3 0 54
4A1C_2 0.00 0.00 0.00 0 11777 5 1 3 1 33
4AOB_A 0.35 0.14 0.86 6 4364 1 0 1 0 36
4ENB_A 0.30 0.16 0.60 3 1270 2 0 2 0 16
4ENC_A 0.30 0.16 0.60 3 1321 2 0 2 0 16

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Matthews Correlation Coeffient, Sensitivity and Positive Predictive Value have been calculated based on the paper by Gardener & Giegerich, 2004.