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Table of contents:

  1. Overview

  2. Performance Plots

  3. Performance of PETfold_pre2.0(seed) - scored higher in this pairwise comparison

  4. Performance of Cylofold - scored lower in this pairwise comparison

  5. Compile and download dataset for PETfold_pre2.0(seed) & Cylofold [.zip] - may take several seconds...


Overview

Metric PETfold_pre2.0(seed) Cylofold
MCC 0.651 > 0.601
Average MCC ± 95% Confidence Intervals 0.610 ± 0.172 < 0.651 ± 0.231
Sensitivity 0.521 > 0.497
Positive Predictive Value 0.821 > 0.735
Total TP 87 > 83
Total TN 14751 > 14744
Total FP 21 < 31
Total FP CONTRA 3 = 3
Total FP INCONS 16 < 27
Total FP COMP 2 > 1
Total FN 80 < 84
P-value 0.0

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Performance plots


  1. Comparison of performance of PETfold_pre2.0(seed) and Cylofold. Positive Predictive Value (PPV) is plotted against sensitivity. Each dot represents a single test of each method. See tables below for raw data (individual counts for PETfold_pre2.0(seed) and Cylofold).

  2. Comparison of average Matthews Correlation Coefficients (MCCs) for PETfold_pre2.0(seed) and Cylofold. The whiskers correspond to 95% confidence intervals (CIs). 'n' denotes the number of MCCs used to calculate average MCCs and CIs. See tables below for raw data (individual counts for PETfold_pre2.0(seed) and Cylofold).

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Performance of PETfold_pre2.0(seed) - scored higher in this pairwise comparison

1. Total counts & total scores for PETfold_pre2.0(seed)

Total Base Pair Counts
Total TP 87
Total TN 14751
Total FP 21
Total FP CONTRA 3
Total FP INCONS 16
Total FP COMP 2
Total FN 80
Total Scores
MCC 0.651
Average MCC ± 95% Confidence Intervals 0.610 ± 0.172
Sensitivity 0.521
Positive Predictive Value 0.821
Nr of predictions 6

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2. Individual counts for PETfold_pre2.0(seed) [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
2LC8_A 0.40 0.30 0.55 6 1529 5 0 5 0 14
3J16_L 0.82 0.70 0.95 21 2753 1 0 1 0 9
3UZL_B 0.72 0.54 0.95 20 3549 2 1 0 1 17
4AOB_A 0.72 0.57 0.92 24 4345 3 0 2 1 18
4ENB_A 0.50 0.42 0.62 8 1262 5 1 4 0 11
4ENC_A 0.50 0.42 0.62 8 1313 5 1 4 0 11

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Performance of Cylofold - scored lower in this pairwise comparison

1. Total counts & total scores for Cylofold

Total Base Pair Counts
Total TP 83
Total TN 14744
Total FP 31
Total FP CONTRA 3
Total FP INCONS 27
Total FP COMP 1
Total FN 84
Total Scores
MCC 0.601
Average MCC ± 95% Confidence Intervals 0.651 ± 0.231
Sensitivity 0.497
Positive Predictive Value 0.735
Nr of predictions 6

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2. Individual counts for Cylofold [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
2LC8_A 0.61 0.55 0.69 11 1524 5 0 5 0 9
3J16_L 0.75 0.57 1.00 17 2758 0 0 0 0 13
3UZL_B 0.45 0.38 0.54 14 3544 12 1 11 0 23
4AOB_A 0.35 0.26 0.48 11 4348 13 1 11 1 31
4ENB_A 0.89 0.79 1.00 15 1260 0 0 0 0 4
4ENC_A 0.86 0.79 0.94 15 1310 1 1 0 0 4

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Matthews Correlation Coeffient, Sensitivity and Positive Predictive Value have been calculated based on the paper by Gardener & Giegerich, 2004.