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Table of contents:

  1. Overview

  2. Performance Plots

  3. Performance of PETfold_pre2.0(seed) - scored higher in this pairwise comparison

  4. Performance of MCFold - scored lower in this pairwise comparison

  5. Compile and download dataset for PETfold_pre2.0(seed) & MCFold [.zip] - may take several seconds...


Overview

Metric PETfold_pre2.0(seed) MCFold
MCC 0.663 > 0.441
Average MCC ± 95% Confidence Intervals 0.603 ± 0.187 > 0.426 ± 0.216
Sensitivity 0.549 > 0.469
Positive Predictive Value 0.807 > 0.423
Total TP 96 > 82
Total TN 25718 > 25643
Total FP 29 < 133
Total FP CONTRA 2 < 16
Total FP INCONS 21 < 96
Total FP COMP 6 < 21
Total FN 79 < 93
P-value 0.0

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Performance plots


  1. Comparison of performance of PETfold_pre2.0(seed) and MCFold. Positive Predictive Value (PPV) is plotted against sensitivity. Each dot represents a single test of each method. See tables below for raw data (individual counts for PETfold_pre2.0(seed) and MCFold).

  2. Comparison of average Matthews Correlation Coefficients (MCCs) for PETfold_pre2.0(seed) and MCFold. The whiskers correspond to 95% confidence intervals (CIs). 'n' denotes the number of MCCs used to calculate average MCCs and CIs. See tables below for raw data (individual counts for PETfold_pre2.0(seed) and MCFold).

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Performance of PETfold_pre2.0(seed) - scored higher in this pairwise comparison

1. Total counts & total scores for PETfold_pre2.0(seed)

Total Base Pair Counts
Total TP 96
Total TN 25718
Total FP 29
Total FP CONTRA 2
Total FP INCONS 21
Total FP COMP 6
Total FN 79
Total Scores
MCC 0.663
Average MCC ± 95% Confidence Intervals 0.603 ± 0.187
Sensitivity 0.549
Positive Predictive Value 0.807
Nr of predictions 6

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2. Individual counts for PETfold_pre2.0(seed) [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
2LC8_A 0.40 0.30 0.55 6 1529 5 0 5 0 14
3J16_L 0.82 0.70 0.95 21 2753 1 0 1 0 9
4A1C_3 0.83 0.70 0.97 38 7101 1 0 1 0 16
4A1C_2 0.57 0.45 0.71 15 11760 12 0 6 6 18
4ENB_A 0.50 0.42 0.62 8 1262 5 1 4 0 11
4ENC_A 0.50 0.42 0.62 8 1313 5 1 4 0 11

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Performance of MCFold - scored lower in this pairwise comparison

1. Total counts & total scores for MCFold

Total Base Pair Counts
Total TP 82
Total TN 25643
Total FP 133
Total FP CONTRA 16
Total FP INCONS 96
Total FP COMP 21
Total FN 93
Total Scores
MCC 0.441
Average MCC ± 95% Confidence Intervals 0.426 ± 0.216
Sensitivity 0.469
Positive Predictive Value 0.423
Nr of predictions 6

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2. Individual counts for MCFold [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
2LC8_A 0.41 0.45 0.39 9 1517 16 0 14 2 11
3J16_L 0.45 0.47 0.44 14 2743 19 1 17 1 16
4A1C_3 0.68 0.67 0.71 36 7089 17 1 14 2 18
4A1C_2 0.13 0.15 0.11 5 11735 56 10 31 15 28
4ENB_A 0.61 0.63 0.60 12 1255 8 2 6 0 7
4ENC_A 0.28 0.32 0.27 6 1304 17 2 14 1 13

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Matthews Correlation Coeffient, Sensitivity and Positive Predictive Value have been calculated based on the paper by Gardener & Giegerich, 2004.