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Table of contents:

  1. Overview

  2. Performance Plots

  3. Performance of PETfold_pre2.0(seed) - scored higher in this pairwise comparison

  4. Performance of Murlet(20) - scored lower in this pairwise comparison

  5. Compile and download dataset for PETfold_pre2.0(seed) & Murlet(20) [.zip] - may take several seconds...


Overview

Metric PETfold_pre2.0(seed) Murlet(20)
MCC 0.678 > 0.496
Average MCC ± 95% Confidence Intervals 0.625 ± 0.179 > 0.489 ± 0.253
Sensitivity 0.557 > 0.353
Positive Predictive Value 0.830 > 0.702
Total TP 93 > 59
Total TN 25781 < 25809
Total FP 26 < 30
Total FP CONTRA 2 = 2
Total FP INCONS 17 < 23
Total FP COMP 7 > 5
Total FN 74 < 108
P-value 0.0

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Performance plots


  1. Comparison of performance of PETfold_pre2.0(seed) and Murlet(20). Positive Predictive Value (PPV) is plotted against sensitivity. Each dot represents a single test of each method. See tables below for raw data (individual counts for PETfold_pre2.0(seed) and Murlet(20)).

  2. Comparison of average Matthews Correlation Coefficients (MCCs) for PETfold_pre2.0(seed) and Murlet(20). The whiskers correspond to 95% confidence intervals (CIs). 'n' denotes the number of MCCs used to calculate average MCCs and CIs. See tables below for raw data (individual counts for PETfold_pre2.0(seed) and Murlet(20)).

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Performance of PETfold_pre2.0(seed) - scored higher in this pairwise comparison

1. Total counts & total scores for PETfold_pre2.0(seed)

Total Base Pair Counts
Total TP 93
Total TN 25781
Total FP 26
Total FP CONTRA 2
Total FP INCONS 17
Total FP COMP 7
Total FN 74
Total Scores
MCC 0.678
Average MCC ± 95% Confidence Intervals 0.625 ± 0.179
Sensitivity 0.557
Positive Predictive Value 0.830
Nr of predictions 5

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2. Individual counts for PETfold_pre2.0(seed) [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
4A1C_3 0.83 0.70 0.97 38 7101 1 0 1 0 16
4A1C_2 0.57 0.45 0.71 15 11760 12 0 6 6 18
4AOB_A 0.72 0.57 0.92 24 4345 3 0 2 1 18
4ENB_A 0.50 0.42 0.62 8 1262 5 1 4 0 11
4ENC_A 0.50 0.42 0.62 8 1313 5 1 4 0 11

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Performance of Murlet(20) - scored lower in this pairwise comparison

1. Total counts & total scores for Murlet(20)

Total Base Pair Counts
Total TP 59
Total TN 25809
Total FP 30
Total FP CONTRA 2
Total FP INCONS 23
Total FP COMP 5
Total FN 108
Total Scores
MCC 0.496
Average MCC ± 95% Confidence Intervals 0.489 ± 0.253
Sensitivity 0.353
Positive Predictive Value 0.702
Nr of predictions 5

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2. Individual counts for Murlet(20) [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
4A1C_3 0.59 0.41 0.85 22 7114 4 0 4 0 32
4A1C_2 0.17 0.15 0.20 5 11756 24 2 18 4 28
4AOB_A 0.72 0.55 0.96 23 4347 2 0 1 1 19
4ENB_A 0.46 0.21 1.00 4 1271 0 0 0 0 15
4ENC_A 0.51 0.26 1.00 5 1321 0 0 0 0 14

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Matthews Correlation Coeffient, Sensitivity and Positive Predictive Value have been calculated based on the paper by Gardener & Giegerich, 2004.