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Table of contents:

  1. Overview

  2. Performance Plots

  3. Performance of PETfold_pre2.0(seed) - scored higher in this pairwise comparison

  4. Performance of RDfolder - scored lower in this pairwise comparison

  5. Compile and download dataset for PETfold_pre2.0(seed) & RDfolder [.zip] - may take several seconds...


Overview

Metric PETfold_pre2.0(seed) RDfolder
MCC 0.634 > 0.281
Average MCC ± 95% Confidence Intervals 0.589 ± 0.216 > 0.284 ± 0.230
Sensitivity 0.515 > 0.215
Positive Predictive Value 0.788 > 0.384
Total TP 67 > 28
Total TN 11202 < 11214
Total FP 19 < 46
Total FP CONTRA 2 < 3
Total FP INCONS 16 < 42
Total FP COMP 1 = 1
Total FN 63 < 102
P-value 0.0

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Performance plots


  1. Comparison of performance of PETfold_pre2.0(seed) and RDfolder. Positive Predictive Value (PPV) is plotted against sensitivity. Each dot represents a single test of each method. See tables below for raw data (individual counts for PETfold_pre2.0(seed) and RDfolder).

  2. Comparison of average Matthews Correlation Coefficients (MCCs) for PETfold_pre2.0(seed) and RDfolder. The whiskers correspond to 95% confidence intervals (CIs). 'n' denotes the number of MCCs used to calculate average MCCs and CIs. See tables below for raw data (individual counts for PETfold_pre2.0(seed) and RDfolder).

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Performance of PETfold_pre2.0(seed) - scored higher in this pairwise comparison

1. Total counts & total scores for PETfold_pre2.0(seed)

Total Base Pair Counts
Total TP 67
Total TN 11202
Total FP 19
Total FP CONTRA 2
Total FP INCONS 16
Total FP COMP 1
Total FN 63
Total Scores
MCC 0.634
Average MCC ± 95% Confidence Intervals 0.589 ± 0.216
Sensitivity 0.515
Positive Predictive Value 0.788
Nr of predictions 5

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2. Individual counts for PETfold_pre2.0(seed) [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
2LC8_A 0.40 0.30 0.55 6 1529 5 0 5 0 14
3J16_L 0.82 0.70 0.95 21 2753 1 0 1 0 9
4AOB_A 0.72 0.57 0.92 24 4345 3 0 2 1 18
4ENB_A 0.50 0.42 0.62 8 1262 5 1 4 0 11
4ENC_A 0.50 0.42 0.62 8 1313 5 1 4 0 11

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Performance of RDfolder - scored lower in this pairwise comparison

1. Total counts & total scores for RDfolder

Total Base Pair Counts
Total TP 28
Total TN 11214
Total FP 46
Total FP CONTRA 3
Total FP INCONS 42
Total FP COMP 1
Total FN 102
Total Scores
MCC 0.281
Average MCC ± 95% Confidence Intervals 0.284 ± 0.230
Sensitivity 0.215
Positive Predictive Value 0.384
Nr of predictions 5

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2. Individual counts for RDfolder [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
2LC8_A -0.01 0.00 0.00 0 1526 14 2 12 0 20
3J16_L 0.22 0.17 0.31 5 2759 11 0 11 0 25
4AOB_A 0.35 0.26 0.48 11 4348 13 1 11 1 31
4ENB_A 0.43 0.32 0.60 6 1265 4 0 4 0 13
4ENC_A 0.43 0.32 0.60 6 1316 4 0 4 0 13

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Matthews Correlation Coeffient, Sensitivity and Positive Predictive Value have been calculated based on the paper by Gardener & Giegerich, 2004.