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Table of contents:

  1. Overview

  2. Performance Plots

  3. Performance of PETfold_pre2.0(seed) - scored higher in this pairwise comparison

  4. Performance of TurboFold(seed) - scored lower in this pairwise comparison

  5. Compile and download dataset for PETfold_pre2.0(seed) & TurboFold(seed) [.zip] - may take several seconds...


Overview

Metric PETfold_pre2.0(seed) TurboFold(seed)
MCC 0.651 > 0.460
Average MCC ± 95% Confidence Intervals 0.588 ± 0.167 > 0.454 ± 0.321
Sensitivity 0.529 > 0.380
Positive Predictive Value 0.805 > 0.563
Total TP 99 > 71
Total TN 27310 > 27307
Total FP 31 < 65
Total FP CONTRA 2 < 7
Total FP INCONS 22 < 48
Total FP COMP 7 < 10
Total FN 88 < 116
P-value 0.0

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Performance plots


  1. Comparison of performance of PETfold_pre2.0(seed) and TurboFold(seed). Positive Predictive Value (PPV) is plotted against sensitivity. Each dot represents a single test of each method. See tables below for raw data (individual counts for PETfold_pre2.0(seed) and TurboFold(seed)).

  2. Comparison of average Matthews Correlation Coefficients (MCCs) for PETfold_pre2.0(seed) and TurboFold(seed). The whiskers correspond to 95% confidence intervals (CIs). 'n' denotes the number of MCCs used to calculate average MCCs and CIs. See tables below for raw data (individual counts for PETfold_pre2.0(seed) and TurboFold(seed)).

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Performance of PETfold_pre2.0(seed) - scored higher in this pairwise comparison

1. Total counts & total scores for PETfold_pre2.0(seed)

Total Base Pair Counts
Total TP 99
Total TN 27310
Total FP 31
Total FP CONTRA 2
Total FP INCONS 22
Total FP COMP 7
Total FN 88
Total Scores
MCC 0.651
Average MCC ± 95% Confidence Intervals 0.588 ± 0.167
Sensitivity 0.529
Positive Predictive Value 0.805
Nr of predictions 6

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2. Individual counts for PETfold_pre2.0(seed) [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
2LC8_A 0.40 0.30 0.55 6 1529 5 0 5 0 14
4A1C_3 0.83 0.70 0.97 38 7101 1 0 1 0 16
4A1C_2 0.57 0.45 0.71 15 11760 12 0 6 6 18
4AOB_A 0.72 0.57 0.92 24 4345 3 0 2 1 18
4ENB_A 0.50 0.42 0.62 8 1262 5 1 4 0 11
4ENC_A 0.50 0.42 0.62 8 1313 5 1 4 0 11

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Performance of TurboFold(seed) - scored lower in this pairwise comparison

1. Total counts & total scores for TurboFold(seed)

Total Base Pair Counts
Total TP 71
Total TN 27307
Total FP 65
Total FP CONTRA 7
Total FP INCONS 48
Total FP COMP 10
Total FN 116
Total Scores
MCC 0.460
Average MCC ± 95% Confidence Intervals 0.454 ± 0.321
Sensitivity 0.380
Positive Predictive Value 0.563
Nr of predictions 6

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2. Individual counts for TurboFold(seed) [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
2LC8_A -0.01 0.00 0.00 0 1525 15 2 13 0 20
4A1C_3 0.69 0.57 0.84 31 7103 6 0 6 0 23
4A1C_2 0.15 0.15 0.15 5 11748 37 3 25 9 28
4AOB_A 0.56 0.40 0.77 17 4349 6 1 4 1 25
4ENB_A 0.69 0.47 1.00 9 1266 0 0 0 0 10
4ENC_A 0.65 0.47 0.90 9 1316 1 1 0 0 10

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Matthews Correlation Coeffient, Sensitivity and Positive Predictive Value have been calculated based on the paper by Gardener & Giegerich, 2004.