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Table of contents:

  1. Overview

  2. Performance Plots

  3. Performance of PPfold(20) - scored higher in this pairwise comparison

  4. Performance of Murlet(seed) - scored lower in this pairwise comparison

  5. Compile and download dataset for PPfold(20) & Murlet(seed) [.zip] - may take several seconds...


Overview

Metric PPfold(20) Murlet(seed)
MCC 0.603 > 0.520
Average MCC ± 95% Confidence Intervals 0.582 ± 0.207 > 0.525 ± 0.052
Sensitivity 0.455 > 0.296
Positive Predictive Value 0.804 < 0.918
Total TP 86 > 56
Total TN 24773 < 24819
Total FP 26 > 6
Total FP CONTRA 0 < 1
Total FP INCONS 21 > 4
Total FP COMP 5 > 1
Total FN 103 < 133
P-value 0.0

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Performance plots


  1. Comparison of performance of PPfold(20) and Murlet(seed). Positive Predictive Value (PPV) is plotted against sensitivity. Each dot represents a single test of each method. See tables below for raw data (individual counts for PPfold(20) and Murlet(seed)).

  2. Comparison of average Matthews Correlation Coefficients (MCCs) for PPfold(20) and Murlet(seed). The whiskers correspond to 95% confidence intervals (CIs). 'n' denotes the number of MCCs used to calculate average MCCs and CIs. See tables below for raw data (individual counts for PPfold(20) and Murlet(seed)).

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Performance of PPfold(20) - scored higher in this pairwise comparison

1. Total counts & total scores for PPfold(20)

Total Base Pair Counts
Total TP 86
Total TN 24773
Total FP 26
Total FP CONTRA 0
Total FP INCONS 21
Total FP COMP 5
Total FN 103
Total Scores
MCC 0.603
Average MCC ± 95% Confidence Intervals 0.582 ± 0.207
Sensitivity 0.455
Positive Predictive Value 0.804
Nr of predictions 6

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2. Individual counts for PPfold(20) [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
3RKF_A 0.73 0.56 0.95 19 2191 1 0 1 0 15
3SD1_A 0.68 0.52 0.88 22 3891 3 0 3 0 20
4A1C_2 0.21 0.15 0.29 5 11764 16 0 12 4 28
4AOB_A 0.74 0.60 0.93 25 4344 3 0 2 1 17
4ENB_A 0.56 0.37 0.88 7 1267 1 0 1 0 12
4ENC_A 0.58 0.42 0.80 8 1316 2 0 2 0 11

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Performance of Murlet(seed) - scored lower in this pairwise comparison

1. Total counts & total scores for Murlet(seed)

Total Base Pair Counts
Total TP 56
Total TN 24819
Total FP 6
Total FP CONTRA 1
Total FP INCONS 4
Total FP COMP 1
Total FN 133
Total Scores
MCC 0.520
Average MCC ± 95% Confidence Intervals 0.525 ± 0.052
Sensitivity 0.296
Positive Predictive Value 0.918
Nr of predictions 6

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2. Individual counts for Murlet(seed) [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
3RKF_A 0.53 0.35 0.80 12 2196 3 1 2 0 22
3SD1_A 0.47 0.26 0.85 11 3903 2 0 2 0 31
4A1C_2 0.46 0.21 1.00 7 11774 0 0 0 0 26
4AOB_A 0.58 0.33 1.00 14 4357 1 0 0 1 28
4ENB_A 0.56 0.32 1.00 6 1269 0 0 0 0 13
4ENC_A 0.56 0.32 1.00 6 1320 0 0 0 0 13

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Matthews Correlation Coeffient, Sensitivity and Positive Predictive Value have been calculated based on the paper by Gardener & Giegerich, 2004.